Identification of lifestyle patterns, including sleep deprivation, associated with insulin resistance in children: the Healthy Growth Study

被引:32
作者
Androutsos, O. [1 ,2 ]
Moschonis, G. [2 ]
Mavrogianni, C. [2 ]
Roma-Giannikou, E. [1 ]
Chrousos, G. P. [1 ,3 ]
Kanaka-Gantenbein, C. [1 ]
Manios, Y. [2 ]
机构
[1] Univ Athens, Aghia Sophia Childrens Hosp, Dept Paediat 1, Athens, Greece
[2] Harokopio Univ Athens, Dept Nutr & Dietet, Athens 17671, Greece
[3] King Abdulaziz Univ, Jeddah 21413, Saudi Arabia
关键词
lifestyle; patterns; insulin resistance; children; PHYSICAL-ACTIVITY; DIETARY PATTERNS; PLASMA-GLUCOSE; OBESITY; WEIGHT; PREVALENCE; OVERWEIGHT; CHILDHOOD; RISK; ADOLESCENTS;
D O I
10.1038/ejcn.2013.280
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
BACKGROUND/OBJECTIVES: Although diet, physical activity (PA), sedentary behavior and sleep deprivation are factors that have been individually associated with insulin resistance (IR) in childhood, the combined effect of these lifestyle behaviors has not been examined yet. The current study aimed to examine the association of lifestyle patterns with IR, combining all these indices, in children. SUBJECTS/METHODS: Socio-economic, demographic, anthropometric (body weight, height and waist circumference), biochemical (plasma glucose and serum insulin), clinical (pubertal stage) and lifestyle (dietary intake, PA level and sleeping habits) data were collected from a representative sample of 2026 children (50.1% girls) aged 9-13 years in Greece. Homeostasis model assessment (HOMA-IR) was calculated, and principal component analysis was used to identify lifestyle patterns, combining all these lifestyle indices. RESULTS: In multivariable regression analyses, the lifestyle pattern characterized by more screen time, shorter sleep duration and higher consumption of sugared beverages was positively associated with HOMA-IR (beta = 0.043; P = 0.040), whereas the pattern characterized by more time spent on moderate-to-vigorous PA (MVPA) and more frequent eating occasions was inversely associated with HOMA-IR (beta = - 0.061; P = 0.003). In logistic regression analyses, children with 72.2 min/day of MVPA and 5.05 eating occasions/day and children with 141.8 min/day of MVPA and 5.22 eating occasions/day were less likely of being insulin resistant based on HOMA-IR, compared with children with 20.0 min/day of MVPA and 4.09 eating occasions/day. CONCLUSIONS: A lifestyle pattern of >72 min of MVPA and 5 eating occasions/day was associated with reduced likelihood of IR in children.
引用
收藏
页码:344 / 349
页数:6
相关论文
共 32 条
  • [1] THE EFFECTS OF SUCROSE, FRUCTOSE, AND HIGH-FRUCTOSE CORN SYRUP MEALS ON PLASMA-GLUCOSE AND INSULIN IN NON-INSULIN-DEPENDENT DIABETIC SUBJECTS
    AKGUN, S
    ERTEL, NH
    [J]. DIABETES CARE, 1985, 8 (03) : 279 - 283
  • [2] Subjective sleep duration and quality influence diet composition and circulating adipocytokines and ghrelin levels in teen-age girls
    Al-Disi, Dara
    Al-Daghri, Nasser
    Khanam, Latifa
    Al-Othman, Abdulaziz
    Al-Saif, Mohammad
    Sabico, Shaun
    Chrousos, George
    [J]. ENDOCRINE JOURNAL, 2010, 57 (10) : 915 - 923
  • [3] Association of Breakfast Skipping With Visceral Fat and Insulin Indices in Overweight Latino Youth
    Alexander, Katharine E.
    Ventura, Emily E.
    Spruijt-Metz, Donna
    Weigensberg, Marc J.
    Goran, Michael I.
    Davis, Jaimie N.
    [J]. OBESITY, 2009, 17 (08) : 1528 - 1533
  • [4] Exercise and insulin sensitivity: A review
    Borghouts, LB
    Keizer, HA
    [J]. INTERNATIONAL JOURNAL OF SPORTS MEDICINE, 2000, 21 (01) : 1 - 12
  • [5] Sugar-Sweetened Beverage Intake Trends in US Adolescents and Their Association with Insulin Resistance-Related Parameters
    Bremer, Andrew A.
    Auinger, Peggy
    Byrd, Robert S.
    [J]. JOURNAL OF NUTRITION AND METABOLISM, 2010, 2010
  • [6] Differences in Weight Status and Energy-Balance Related Behaviors among Schoolchildren across Europe: The ENERGY-Project
    Brug, Johannes
    van Stralen, Maartje M.
    te Velde, Saskia J.
    Chinapaw, Mai J. M.
    De Bourdeaudhuij, Ilse
    Lien, Nanna
    Bere, Elling
    Maskini, Victoria
    Singh, Amika S.
    Maes, Lea
    Moreno, Luis
    Jan, Natasa
    Kovacs, Eva
    Lobstein, Tim
    Manios, Yannis
    [J]. PLOS ONE, 2012, 7 (04):
  • [7] Tracking of cardiometabolic risk factor clustering from childhood to adulthood
    Camhi, Sarah M.
    Katzmarzyk, Peter T.
    [J]. INTERNATIONAL JOURNAL OF PEDIATRIC OBESITY, 2010, 5 (02): : 122 - 129
  • [8] Establishing a standard definition for child overweight and obesity worldwide: international survey
    Cole, TJ
    Bellizzi, MC
    Flegal, KM
    Dietz, WH
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 2000, 320 (7244): : 1240 - 1243
  • [9] Pediatric obesity and insulin resistance: Chronic disease risk and implications for treatment and prevention beyond body weight modification
    Cruz, ML
    Shaibi, GQ
    Weigensberg, MJ
    Spruijt-Metz, D
    Ball, GDC
    Goran, MI
    [J]. ANNUAL REVIEW OF NUTRITION, 2005, 25 : 435 - 468
  • [10] Dietary patterns, insulin resistance, and prevalence of the metabolic syndrome in women
    Esmaillzadeh, Ahmad
    Kimiagar, Masoud
    Mehrabi, Yadollah
    Azadbakht, Leila
    Hu, Frank B.
    Willett, Walter C.
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 2007, 85 (03) : 910 - 918