Structure of the human gene encoding the MAp19 and MASP-2 proteins

被引:0
作者
Park, DK
Kim, B
Baek, KH
Yoon, JS
机构
[1] Kyung Hee Univ, Dept Genet Engn, Yongin 449701, South Korea
[2] Kyung Hee Univ, Inst Genet Engn, Yongin 449701, South Korea
来源
KOREAN JOURNAL OF GENETICS | 2002年 / 24卷 / 03期
关键词
MASP-2; Map19; gene structure; human;
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
We have characterized the complete structure of the human gene encoding the MAp19 and MASP-2 proteins which are involved in one of the important innate immune defense mechanisms of the hosts. The mRNA species encoding MASP-2 and MAp19 are encoded by the alternative splicing and polyadenylation from a single structural gene. The gene consists of 12 exons. The four exons are common to both MAp19 and MASP-2 transcripts, one exon is specific for MAp19 transcript, and seven exons are specific for MASP-2 transcript. The transcription start point was determined by 5'-RACE analysis.
引用
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页码:313 / 318
页数:6
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