Targeting cytotoxic T lymphocytes for cancer immunotherapy

被引：80
|
作者：
Maher, J
Davies, ET
机构：
[1] Guys Hosp, Guys Kings & St Thomass Sch Med, Div Canc Studies, Canc Res UK Breast Canc Biol Grp, London SE1 9RT, England
[2] Kings Coll Hosp London, Rayne Inst, Dept Clin Immunol, London SE5 9NU, England
来源：
BRITISH JOURNAL OF CANCER | 2004年 / 91卷 / 05期
关键词：
CTL; vaccine; adoptive immunotherapy; gene therapy;
D O I：
10.1038/sj.bjc.6602022
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In light of their preeminent role in cellular immunity, there is considerable interest in targeting of cytotoxic T-lymphocytes to cancer. This review summarises the active and passive immunotherapeutic approaches under development to achieve this goal, emphasising how recent advances in tumour immunology and gene transfer have impacted upon this field.
引用
收藏
页码：817 / 821
页数：5
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