Antiepileptic drugs

被引:0
作者
Luis Herranz, Jose [1 ]
机构
[1] Neurol Pediat & Neurofisiol Clin, Santander, Cantabria, Spain
关键词
Antiepileptic drugs; Brivaracetam; Eslicarbazepine acetate; Perampanel; ESLICARBAZEPINE ACETATE; REAL-LIFE; EPILEPSY; BRIVARACETAM; PERAMPANEL; MULTICENTER; MONOTHERAPY; PHARMACOKINETICS; LEVETIRACETAM; CARBAMAZEPINE;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We report the most notable pharmacokinetic and pharmacodynamic characteristics of the antiepileptic drugs commercialised in the last four years (eslicarbazepine acetate, brivaracetam and perampanel). Their efficacy and safety are analysed in open-label clinical trials, which are the ones that reproduce their use in everyday life, without the rigid protocols used in clinical trials.
引用
收藏
页码:S21 / S25
页数:5
相关论文
共 28 条
[1]  
Alarcon H, 2016, 24 C AN AC IB NEUR P
[2]  
Arzimanoglou A, 2018, PEDIAT DRUGS
[3]   Pharmacokinetic/pharmacodynamic evaluation of eslicarbazepine for the treatment of epilepsy [J].
Banach, Monika ;
Borowicz, Kinga K. ;
Czuczwar, Stanislaw J. .
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 2015, 11 (04) :639-648
[4]  
Braakman Hilde M, 2017, Epilepsia Open, V2, P343, DOI 10.1002/epi4.12059
[5]   Preliminary Asian experience of using perampanel in clinical practice [J].
Chiang, Hsing-I ;
Lim, Siew-Na ;
Hsieh, Hsiang-Yao ;
Cheng, Mei-Yun ;
Chang, Chun-Wei ;
Tseng, Wei-En Johnny ;
Li, Han-Tao ;
Lin, Chin-Yin ;
Wu, Tony .
BIOMEDICAL JOURNAL, 2017, 40 (06) :347-354
[6]   Effectiveness and tolerability of perampanel in children and adolescents with refractory epilepsies An Italian observational multicenter study [J].
De Liso, P. ;
Vigevano, F. ;
Specchio, N. ;
De Palma, L. ;
Bonanni, P. ;
Osanni, E. ;
Coppola, G. ;
Parisi, P. ;
Grosso, S. ;
Verrotti, A. ;
Spalice, A. ;
Nicita, F. ;
Zamponi, N. ;
Siliquini, S. ;
Giordano, L. ;
Martelli, P. ;
Guerrini, R. ;
Rosati, A. ;
Ilvento, L. ;
Belcastro, V. ;
Striano, P. ;
Vari, M. S. ;
Capovilla, G. ;
Beccaria, F. ;
Bruni, O. ;
Luchetti, A. ;
Gobbi, G. ;
Russo, A. ;
Pruna, D. ;
Tozzi, A. E. ;
Cusmai, R. .
EPILEPSY RESEARCH, 2016, 127 :93-100
[7]   Genomics-Guided Precise Anti-Epileptic Drug Development [J].
Delanty, Norman ;
Cavallleri, Gianpiero .
NEUROCHEMICAL RESEARCH, 2017, 42 (07) :2084-2088
[8]   Pharmacokinetics and tolerability of eslicarbazepine acetate and oxcarbazepine at steady state in healthy volunteers [J].
Elger, Christian ;
Bialer, Meir ;
Falcao, Amilcar ;
Vaz-da-Silva, Manuel ;
Nunes, Teresa ;
Almeida, Luis ;
Soares-da-Silva, Patricio .
EPILEPSIA, 2013, 54 (08) :1453-1461
[9]  
Gil-Lopez FJ, 2018, ACTA NEUROL SCAND
[10]   A retrospective, multicentre study of perampanel given as monotherapy in routine clinical care in people with epilepsy [J].
Gil-Nagel, Antonio ;
Burd, Sergey ;
Toledo, Manuel ;
Sander, Josemir W. ;
Lebedev, Anna ;
Patten, Anna ;
Laurenz, Antonio .
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2018, 54 :61-66