Male breast cancer: clinical features and multimodal treatment in a retrospective survey analysis at Italian centers

被引：0

作者：

La Verde, Nicla ^{[1
]}

Collova, Elena ^{[2
]}

Lonardi, Sara ^{[3
]}

Generali, Daniele ^{[4
]}

Moretti, Anna ^{[1
]}

Atzori, Francesco ^{[5
]}

Cazzaniga, Marina ^{[6
]}

Saggia, Chiara ^{[7
]}

Tondulli, Luca ^{[8
]}

Marcon, Ilaria ^{[9
,10
]}

Gentile, Anna Lisa ^{[11
]}

Rossello, Rosalba ^{[12
]}

Martelli, Olga ^{[13
]}

Aglione, Stefania ^{[14
]}

Farina, Gabriella ^{[1
]}

Cinquini, Michela ^{[15
]}

Garassino, Marina ^{[16
]}

机构：

[1] Azienda Osped Fatebenefratelli & Oftalm, Dept Oncol, I-20121 Milan, Italy

[2] Hosp Legnano, Div Med Oncol, Legnano, Italy

[3] Veneto Oncol Inst IRCCS, Med Oncol Unit 1, Padua, Italy

[4] UO Multidisciplinare Patol Mammaria, Azienda Ist Osp Cremona, Cremona, Italy

[5] AO Univ Cagliari, Med Oncol Unit, Cagliari, Italy

[6] San Gerardo Hosp, Dept Med Oncol, Monza, Italy

[7] Maggiore Hosp, Dept Oncol, Novara, Italy

[8] AO Univ Integrata, Verona Borgo Trento Hosp, Dept Oncol, Verona, Italy

[9] Osped Circolo Varese, Dept Oncol, Varese, Italy

[10] Fdn Macchi, Dept Oncol, Varese, Italy

[11] G Mazzini Hosp, Med Oncol Unit, Teramo, Italy

[12] Policlin Univ G Martino, Dept Human Pathol, Med Oncol & Integrated Therapies Unit, Messina, Italy

[13] AO S Giovanni Addolorata, Med Oncol Unit, Rome, Italy

[14] AO Desio Vimercate, Dept Oncol, Vimercate, MI, Italy

[15] Mario Negri Inst Pharmacol Res, Dept Oncol, Milan, Italy

[16] Fdn IRCCS Ist Nazl Tumori, Med Oncol Unit 1, Milan, Italy

来源：

TUMORI JOURNAL | 2013年 / 99卷 / 05期

关键词：

adjuvant therapy; early breast cancer; male breast cancer; systemic treatments; MANAGEMENT; CARCINOMA;

D O I：

10.1177/030089161309900506

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Aims and background. We report a collection of data about early breast cancer in male patients from 13 Italian institutions. Methods and study design. We obtained data from patient charts and performed statistical analysis. The primary end points were overall survival and disease-free survival. Results. A total of 205 men with invasive breast cancer was identified, with a median age of 66 years. Pathological characteristics were heterogeneous for T stage, N stage and HER2 status. Histological subtype was predominantly ductal infiltrating carcinoma. Most of them were hormone receptor positive. Mastectomy was the most common strategy Postsurgical treatment was not standardized. Patients with large tumors were more likely to be treated with chemotherapy. Disease recurrence was associated with an ER+ and PR+ status. Conclusions., We identified a correlation between relapse and hormone receptor expression, as is the case in female breast cancer.

引用

页码：596 / 600

页数：5

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