PLACENTAL ABNORMALITIES AND PREECLAMPSIA IN TRISOMY 13 PREGNANCIES

被引：30

作者：

Chen, Chih-Ping ^{[1
,2
,3
,4
,5
]}

机构：

[1] Mackay Mem Hosp, Dept Obstet & Gynecol, Taipei, Taiwan

[2] Mackay Mem Hosp, Dept Med Res, Taipei, Taiwan

[3] Asia Univ, Dept Biotechnol, Taichung, Taiwan

[4] China Med Univ, Coll Chinese Med, Sch Chinese Med, Taichung, Taiwan

[5] Natl Yang Ming Univ, Inst Clin & Community Hlth Nursing, Taipei 112, Taiwan

来源：

TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY | 2009年 / 48卷 / 01期

关键词：

COL4A2; periostin; placental abnormalities; preeclampsia; pregnancy; sFItI; trisomy; 13; GROWTH-FACTOR RECEPTOR; TYROSINE KINASE-1; RISK; PATHOPHYSIOLOGY; ULTRASOUND; EXPRESSION; HYPOXIA; OXYGEN; WOMEN; OVEREXPRESSION;

D O I：

10.1016/S1028-4559(09)60028-0

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Women who are carrying a trisomy 13 fetus are prone to have an abnormal placenta as well as to develop preeclampsia in the second and third trimesters. This article provides a comprehensive review of placental abnormalities, such as small placental volume, reduced placental vascularization, a partial molar appearance of the placenta and placental mesenchymal dysplasia, and preeclampsia associated with trisomy 13 pregnancies. The candidate preeclampsia-causing genes on chromosome 13, such as sFIt1, COL4A2 and periostin, are discussed. [Taiwan J Obstet Gynecol 2009;48(1):3-8]

引用

页码：3 / 8

页数：6

共 64 条

[1]

Arizawa M, 1992, Nihon Sanka Fujinka Gakkai Zasshi, V44, P9

[2]

Arizawa Masayoshi, 2002, Congenital Anomalies, V42, P309, DOI 10.1111/j.1741-4520.2002.tb00897.x

[3] First-trimester serum levels of soluble endoglin and soluble fms-like tyrosine kinase-1 as first-trimester markers for late-onset preeclampsia [J].

Baumann, Marc U. ;

Bersinger, Nick A. ;

Mohaupt, Markus G. ;

Raio, Luigi ;

Gerber, Susan ;

Surbek, Daniel V. .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2008, 199 (03) :266.e1-266.e6

[4] Circulating angiogenic proteins in trisomy 13 [J].

Bdolah, Y ;

Palomaki, GE ;

Yaron, Y ;

Bdolah-Abram, T ;

Goldman, M ;

Levine, RJ ;

Sachs, BP ;

Haddow, JE ;

Karumanchi, SA .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2006, 194 (01) :239-245

[5] Angiogenic imbalance in the pathophysiology of preeclampsia: Newer insights [J].

Bdolah, Y ;

Sukhatme, VP ;

Karumanchi, SA .

SEMINARS IN NEPHROLOGY, 2004, 24 (06) :548-556

[6] Co-ordinated expression of MMP-2 and its putative activator, MT1-MMP, in human placentation [J].

Bjorn, SF ;

Hastrup, N ;

Lund, LR ;

Dano, K ;

Larsen, JF ;

Pyke, C .

MOLECULAR HUMAN REPRODUCTION, 1997, 3 (08) :713-723

[7]

BOWER C, 1987, LANCET, V2, P1032

[8]

BOYD PA, 1987, LANCET, V2, P425

[9] Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFβ3 [J].

Caniggia, I ;

Mostachfi, H ;

Winter, J ;

Gassmann, M ;

Lye, SJ ;

Kuliszewski, M ;

Post, M .

JOURNAL OF CLINICAL INVESTIGATION, 2000, 105 (05) :577-587

[10] Evidence supporting a rote for blockade of the vascular endothelial growth factor system in the pathophysiology of preeclampsia -: Young Investigator Award [J].

Chaiworapongsa, T ;

Romero, R ;

Espinoza, J ;

Bujoid, E ;

Kim, YM ;

Goçalves, LF ;

Gomez, R ;

Edwin, S .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2004, 190 (06) :1541-1547

← 1 2 3 4 5 6 7 →