evolution;
G protein-coupled receptor;
neuropeptide;
physiological function;
receptor regulation;
somatostatin;
D O I:
10.1111/j.1471-4159.2004.02402.x
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
This review summarizes the latest advances that have been made to elucidate the somatostatinergic system in respect to somatostatin receptor evolution, the development of receptor agonists/antagonists, receptor regulation, signal transduction, effects on cell proliferation, receptor-receptor or receptor-protein interactions and receptor function.