Associative pullulan gels and their interaction with biological active substances

被引：43
作者：
Mocanu, G [1 ]
Mihai, D [1 ]
Picton, L [1 ]
LeCerf, D [1 ]
Muller, G [1 ]
机构：
[1] Univ Rouen, UMR 6522, Rouen, France
来源：
JOURNAL OF CONTROLLED RELEASE | 2002年 / 83卷 / 01期
关键词：
crosslinked carboxymethylpullulan; hydrophobically modified polysaccharides; immobilized lysozyme;
D O I：
10.1016/S0168-3659(02)00169-4
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
This paper studies the synthesis and properties of anionic and/or amphiphilic pullulan microparticles crosslinked with epichlorohydrine or with sodium trimethaphosphate. The polysaccharide gels were physicochemically characterized and their interaction with enzymes (lysozyme) was studied with the aim to appreciate the performances for separation/purification/immobilization of the enzymes or controlled release drug systems. (C) 2002 Elsevier Science B.V.. All rights reserved.
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收藏
页码：41 / 51
页数：11
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