Raman spectroscopic discrimination of normal and cancerous lung tissues

被引：27

作者：

Sinica, Alla ^{[1
]}

Brozakova, Katerina ^{[1
]}

Bruha, Tomas ^{[2
]}

Votruba, Jiri ^{[2
]}

机构：

[1] Univ Chem & Technol Prague, Dept Analyt Chem, Tech 5, Prague 16628 6, Czech Republic

[2] Charles Univ Prague, Gen Univ Hosp Prague, Pulm Clin 1, Fac Med 1, U Nemocnice 2, Prague 12800 2, Czech Republic

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2019年 / 219卷

关键词：

Raman spectroscopy; Lung tissues; Cancer diagnosis; PCA-WA; INFRARED-ABSORPTION-SPECTRA; VIVO DIAGNOSIS; HEMOGLOBIN; AUTOFLUORESCENCE; BLOOD; OXYHEMOGLOBIN; EXCITATION; MARKERS; FTIR; CELL;

D O I：

10.1016/j.saa.2019.04.055

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

Raman spectroscopy is non-destructive method that allows monitoring of biological tissues with minimal intervention. FT-Raman (lambda(ex) 1064 nm) and NIR-Vis-Raman (lambda(ex) 785 nm) spectroscopic measurements were used in ex vivo analysis of normal. non-cancerous abnormal and cancerous lung tissues. Spectroscopic discrimination of the lung tissue samples was made by the use of the ratio of characteristic bands and multivariate statistical methods (PCA, IDA). The combination of Raman spectroscopy and multivariate statistics may have a diagnostic potential for recognizing of cancer lesions in lung. (C) 2019 Published by Elsevier B.V.

引用

页码：257 / 266

页数：10

共 66 条

[1]

[Anonymous], 247 CDC

[2] Autofluorescence of Condensed Heme Aggregates in Malaria Pigment and Its Synthetic Equivalent Hematin Anhydride (β-Hematin) [J].

Bellemare, Marie-Josee ;

Bohle, D. Scott ;

Brosseau, Colin-Nadeau ;

Georges, Elias ;

Godbout, Marianne ;

Kelly, Jane ;

Leimanis, Mara L. ;

Leonelli, Richard ;

Olivier, Martin ;

Smilkstein, Martin .

JOURNAL OF PHYSICAL CHEMISTRY B, 2009, 113 (24) :8391-8401

[3] Raman, polarized Raman and ultraviolet resonance Raman spectroscopy of nucleic acids and their complexes [J].

Benevides, JM ;

Overman, SA ;

Thomas, GJ .

JOURNAL OF RAMAN SPECTROSCOPY, 2005, 36 (04) :279-299

[4] OPTICAL-ABSORPTION SPECTRA OF DEOXYHEMOGLOBIN AND OXYHEMOGLOBIN IN THE TEMPERATURE-RANGE 300-20-K - RELATION WITH PROTEIN DYNAMICS [J].

CORDONE, L ;

CUPANE, A ;

LEONE, M ;

VITRANO, E .

BIOPHYSICAL CHEMISTRY, 1986, 24 (03) :259-275

[5] Raman spectroscopy of lipids: a review [J].

Czamara, K. ;

Majzner, K. ;

Pacia, M. Z. ;

Kochan, K. ;

Kaczor, A. ;

Baranska, M. .

JOURNAL OF RAMAN SPECTROSCOPY, 2015, 46 (01) :4-20

[6] Near-infrared Raman spectroscopy for estimating biochemical changes associated with different pathological conditions of cervix [J].

Daniel, Amuthachelvi ;

Prakasarao, Aruna ;

Ganesan, Singaravelu .

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2018, 190 :409-416

[7] The Mahalanobis distance [J].

De Maesschalck, R ;

Jouan-Rimbaud, D ;

Massart, DL .

CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 2000, 50 (01) :1-18

[8] Study of the effect of alcohol on single human red blood cells using near-infrared laser tweezers Raman spectroscopy [J].

Deng, JL ;

Wei, Q ;

Zhang, MH ;

Wang, YZ ;

Li, YQ .

JOURNAL OF RAMAN SPECTROSCOPY, 2005, 36 (03) :257-261

[9] RAMAN-SCATTERING OF COLLAGEN, GELATIN, AND ELASTIN [J].

FRUSHOUR, BG ;

KOENIG, JL .

BIOPOLYMERS, 1975, 14 (02) :379-391

[10]

GALAT A, 1980, ACTA BIOCHIM POL, V27, P135

← 1 2 3 4 5 6 7 →