Multidirectional Global Left Ventricular Systolic Function in Normal Subjects and Patients with Hypertension: Multicenter Evaluation

被引：49

作者：

Morris, Daniel A. ^{[1
]}

Otani, Kyoko ^{[2
]}

Bekfani, Tarek ^{[1
]}

Takigiku, Kiyohiro ^{[3
]}

Izumi, Chisato ^{[4
]}

Yuda, Satoshi ^{[5
]}

Sakata, Konomi ^{[6
]}

Ohte, Nobuyuki ^{[7
]}

Tanabe, Kazuaki ^{[8
]}

Friedrich, Katharina ^{[1
]}

Kuehnle, York ^{[1
]}

Nakatani, Satoshi ^{[9
]}

Otsuji, Yutaka ^{[2
]}

Haverkamp, Wilhelm ^{[1
]}

Boldt, Leif-Hendrik ^{[1
]}

Takeuchi, Masaaki ^{[2
]}

机构：

[1] Charite, D-13353 Berlin, Germany

[2] Univ Occupat & Environm Hlth, Sch Med, Kitakyushu, Fukuoka 807, Japan

[3] Nagano Childrens Hosp, Azumino, Japan

[4] Tenri Hosp, Tenri, Nara 632, Japan

[5] Sapporo Med Univ, Sch Med, Sapporo, Hokkaido, Japan

[6] Kyorin Univ, Sch Med, Tokyo, Japan

[7] Nagoya City Univ, Grad Sch Med Sci, Nagoya, Aichi, Japan

[8] Shimane Univ, Fac Med, Izumo, Shimane, Japan

[9] Osaka Univ, Grad Sch Med, Suita, Osaka, Japan

来源：

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY | 2014年 / 27卷 / 05期

关键词：

Strain; Speckle-tracking echocardiography; Systolic function; Left ventricular; SPECKLE-TRACKING ECHOCARDIOGRAPHY; HEART-FAILURE; DIASTOLIC DYSFUNCTION; LONGITUDINAL STRAIN; MYOCARDIAL STRAIN; CONTRACTILITY; DEFORMATION; PERFORMANCE; RECOMMENDATIONS; ANTHRACYCLINE;

D O I：

10.1016/j.echo.2014.01.017

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: The aim of this multicenter study was to determine the normal ranges and the clinical relevance of multidirectional systolic parameters to evaluate global left ventricular (LV) systolic function. Methods: Three hundred twenty-three healthy adult subjects prospectively included at 10 centers and a cohort of 310 patients with hypertension were analyzed. Multidirectional global LV systolic function was analyzed using two-dimensional speckle-tracking echocardiography by means of two indices: longitudinal-circumferential systolic index (the average of longitudinal and circumferential global systolic strain) and global systolic index (the average of longitudinal, circumferential, and radial global systolic strain). Results: The ranges of values of the multidirectional systolic parameters in healthy subjects were -21.22 +/- 2.22% for longitudinal-circumferential systolic index and 29.71 +/- 5.28% for global systolic index. In addition, the lowest expected values of these multidirectional indices were determined in this population (calculated as -1.96 SDs from the mean): -16.86% for longitudinal-circumferential systolic index and 19.36% for global systolic index. Concerning the clinical relevance of these measurements, these indices indicated the presence of subtle LV global systolic dysfunction in patients with hypertension, even though LV global longitudinal systolic strain and LV ejection fraction were normal. Moreover, in these patients, functional class (dyspnea [New York Heart Association classification]) was inversely related to both the longitudinal-circumferential index and the global systolic index. Conclusions: In the present multicenter study analyzing a large cohort of healthy subjects and patients with hypertension, the normal range and the clinical relevance of multidirectional systolic parameters to evaluate global LV systolic function have been determined. (J Am Soc Echocardiogr 2014; 27: 493-500.)

引用

页码：493 / 500

页数：8

共 40 条

[1] Quantitative Analysis of Endocardial and Epicardial Left Ventricular Myocardial Deformation-Comparison of Strain-Encoded Cardiac Magnetic Resonance Imaging with Two-Dimensional Speckle-Tracking Echocardiography [J].