Eosinophilic granuloma of the sacrum treated with radiation therapy: a case report

被引：7

作者：

Bumpass, David B. ^{[1
]}

Park, Andrew ^{[1
]}

Hill, Kirk T. ^{[2
]}

Huang, Jiayi ^{[3
]}

Friedman, Michael V. ^{[4
]}

Zebala, Lukas P. ^{[1
]}

机构：

[1] Washington Univ, Dept Orthopaed Surg, St Louis, MO 63110 USA

[2] Washington Univ, Dept Pathol, St Louis, MO 63110 USA

[3] Washington Univ, Dept Radiat Oncol, St Louis, MO 63110 USA

[4] Washington Univ, Mallinckrodt Inst Radiol, St Louis, MO 63110 USA

来源：

SPINE JOURNAL | 2016年 / 16卷 / 01期

关键词：

Benign bone tumor; Eosinophilic granuloma; Langerhans cell histiocytosis; Radiation therapy; Sacrum; Spine tumor; LANGERHANS-CELL HISTIOCYTOSIS; TERM-FOLLOW-UP; SPINE; MANAGEMENT; CHILDREN; RADIOTHERAPY; DIAGNOSIS; LESIONS;

D O I：

10.1016/j.spinee.2015.09.022

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

BACKGROUND CONTEXT: Eosinophilic granulomas (EGs) of the sacrum have been reported in fewer than 10 patients. Treatment algorithms for these tumors remain poorly defined; there are no reports of treating solitary sacral EG with radiation therapy (RT). PURPOSE: This study aimed to describe the presentation, treatment, and outcome of sacral EG in an adult patient with intractable pain and radiculopathy, treated in a novel fashion with RT. STUDY DESIGN/SETTING: The study design was a case report from a tertiary cancer referral center. METHODS: Patient records, imaging, and pathology were reviewed. RESULTS: A 35-year-old man received 20 Gy of radiation to his S1 EG lesion. He subsequently developed vertebra plana of S1 causing symptomatic L5-S1 stenosis, but 15 months after RT treatment was free of pain or tumor recurrence. CONCLUSION: Radiation therapy is an effective treatment option for sacral EG causing severe axial pain and neural impingement. (C) 2015 Elsevier Inc. All rights reserved.

引用

页码：E53 / E57

页数：5

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