Trace lithium in Texas tap water is negatively associated with all-cause mortality and premature death

被引：21

作者：

Fajardo, Val Andrew ^{[1
,2
]}

LeBlanc, Paul J. ^{[1
,2
]}

Fajardo, Val Andrei ^{[3
]}

机构：

[1] Brock Univ, Dept Hlth Sci, St Catharines, ON L2S 3A1, Canada

[2] Brock Univ, Ctr Bone & Muscle Hlth, St Catharines, ON L2S 3A1, Canada

[3] Univ Waterloo, Dept Actuarial Sci, Waterloo, ON N2L 3G1, Canada

来源：

APPLIED PHYSIOLOGY NUTRITION AND METABOLISM | 2018年 / 43卷 / 04期

基金：

加拿大自然科学与工程研究理事会;

关键词：

lifespan; longevity; GSK3; lithium; healthspan; CAENORHABDITIS-ELEGANS; RISK-FACTORS; SUICIDE;

D O I：

10.1139/apnm-2017-0653

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Lithium in tap water was previously found to have life-extending effects across 18 Japanese municipalities. Using a larger dataset with several Texas counties, our study shows that lithium concentrations in tap water are negatively associated with all-cause mortality (r = -0.18, p = 0.006, 232 counties) and years of potential life lost (r = -0.22, p = 0.001, 214 counties). Thus, our present findings extend and reinforce lithium's purported life-prolonging effect in humans.

引用

页码：412 / 414

页数：3

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