Graphene quantum dot modified screen printed immunosensor for the determination of parathion

被引：69
作者：
Mehta, Jyotsana [1 ,2 ]
Bhardwaj, Neha [1 ,2 ]
Bhardwaj, Sanjeev K. [1 ,2 ]
Tuteja, Satish K. [3 ]
Vinayak, Priya [4 ]
Paul, A. K. [5 ]
Kim, Ki-Hyun [6 ]
Deep, Akash [1 ,2 ]
机构：
[1] Cent Sci Instruments Org CSIR CSIO, Nanosci & Nanotechnol Lab, Sect 30 C, Chandigarh 160030, India
[2] Acad Sci & Innovat Res CSIR CSIO, Sect 30 C, Chandigarh 160030, India
[3] Univ Guelph, Sch Engn, BioNano Lab, Guelph, ON N1G 2W1, Canada
[4] Indian Inst Technol, Dept Chem Engn, Delhi 110016, India
[5] DAV Univ, Jalandhar, Punjab, India
[6] Hanyang Univ, Dept Civil & Environm Engn, 222 Wangsimni Ro, Seoul 04763, South Korea
来源：
ANALYTICAL BIOCHEMISTRY | 2017年 / 523卷
基金：
新加坡国家研究基金会;
关键词：
Graphene quantum dots; Immunosensor; Electrochemical impedance spectroscopy; Parathion; Screen-printed electrode; ELECTROCHEMICAL IMMUNOSENSOR; IMPEDANCE SPECTROSCOPY; SENSITIVE DETECTION; HYDROGEN-PEROXIDE; CARBON ELECTRODE; SENSOR; BIOSENSOR; COMPOSITE; OXIDE; ACETYLCHOLINESTERASE;
D O I：
10.1016/j.ab.2017.01.026
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The widespread use of pesticides has immense effect on increased crop productions. However, they are also responsible for posing detrimental health hazards and/or for contaminating the environment with chemical residues. A routine and an on-field detection of pesticide residues in different food, water, and soil samples has become a need of the hour for which biosensors can offer a viable alternative. The present work reports a functionalized graphene quantum dot (GQD) based screen printed electro-chemical immunosensor for the detection of parathion. The application of GQDs has permitted the realization of a sensitive, robust, and reproducible sensor unlike those carried out earlier for the similar purposes. This immunosensor exhibited a dynamic linear response for parathion within the range of 0.01 -10(6) ng/L with a very low detection limit of 46 pg/L. According to the analysis of potential interferences, the proposed sensor was specifically detecting parathion even in the presence of its metabolite, paraoxon. The investigations of the proposed sensing approach with respect to stability, response reproducibility, and regeneration have fully supported its potential practical applicability. (C) 2017 Elsevier Inc. All rights reserved.
引用
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页码：1 / 9
页数：9
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