Manufacturing and characterization of 3-D hydroxyapatite bone tissue engineering scaffolds

被引:38
作者
Chu, TMG [1 ]
Hollister, SJ
Halloran, JW
Feinberg, SE
Orton, DG
机构
[1] Univ Michigan, Dept Biomed Engn, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Sch Dent, Ann Arbor, MI 48109 USA
[3] Univ Michigan, Dept Mat Sci & Engn, Ann Arbor, MI 48109 USA
[4] Univ Michigan, Dept Surg, Ann Arbor, MI 48109 USA
[5] Terumo Cardiovasc Syst, Ann Arbor, MI USA
来源
REPARATIVE MEDICINE: GROWING TISSUES AND ORGANS | 2002年 / 961卷
关键词
bioscaffolds; hydroxyapetite; bone tissue engineering;
D O I
10.1111/j.1749-6632.2002.tb03061.x
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Internal architecture has a direct impact on the mechanical and biological behaviors of porous hydroxyapatite (HA) implants. However, traditional processing methods provide very minimal control in this regard. This paper reviews a novel processing technique developed in our laboratory for fabricating scaffolds with controlled internal architectures. The preliminary mechanical property and in vivo evaluation of these scaffolds are also presented.
引用
收藏
页码:114 / 117
页数:4
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