One-pot Synthesis of 2-Substituted Imidazo[2,1-b][1,3]benzothiazoles via Coupling-Cyclization Under Pd-Cu Catalysis in Water

被引：4

作者：

Bakherad, Mohammad ^{[1
]}

Keivanloo, Ali ^{[1
]}

Hashemi, Mahdieh ^{[1
]}

机构：

[1] Shahrood Univ Technol, Fac Chem, Shahrood 3619995161, Iran

来源：

LETTERS IN ORGANIC CHEMISTRY | 2009年 / 6卷 / 02期

关键词：

Sonogashira coupling; aryl iodide; imidazo[2,1-b][1,3]benzothiazole; Pd-catalyzed; potassium carbonate; sodium lauryl sulfate; POTENTIAL ANTITUMOR AGENTS; COPPER-FREE; SONOGASHIRA REACTION; TERMINAL ALKYNES; ARYL HALIDES; ROOM-TEMPERATURE; AQUEOUS-MEDIA; ALKYNYLATION; ACETYLENES; CHEMISTRY;

D O I：

10.2174/157017809787582717

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of 2-imino-3-(2-propynyl)-1,3-benzothiazole with various aryl iodides, catalyzed by Pd-Cu, in the presence of sodium lauryl sulfate as the surfactant and potassium carbonate as the base, in water, leads to the formation of 2-substituted imidazo[ 2,1-b][ 1,3] benzothiazoles.

引用

页码：165 / 170

页数：6

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