Vehicle-saving theranostic probes based on hydrophobic iron oxide nanoclusters using doxorubicin as a phase transfer agent for MRI and chemotherapy

被引：7
作者：
Cao, Yanbing [1 ,2 ]
Min, Juan [3 ]
Zheng, Dongye [4 ]
Li, Jiong [4 ]
Xue, Yanan [1 ,2 ]
Yu, Faquan [1 ,2 ]
Wu, Ming [5 ]
机构：
[1] Wuhan Inst Technol, Hubei Engn Res Ctr Adv Fine Chem, Hubei Key Lab Novel Reactor & Green Chem Technol, Key Lab Green Chem Proc,Minist Educ, Wuhan 430205, Hubei, Peoples R China
[2] Wuhan Inst Technol, Sch Chem Engn & Pharm, Wuhan 430205, Hubei, Peoples R China
[3] Fujian Med Univ, Mengchao Hepatobiliary Hosp, United Innovat Mengchao Hepatobiliary Technol Key, Fuzhou 350025, Fujian, Peoples R China
[4] Chinese Acad Sci, Fujian Inst Res Struct Matter, Key Lab Design & Assembly Funct Nanostruct, Fuzhou 350002, Fujian, Peoples R China
[5] Chinese Acad Sci, Wuhan Inst Virol, Wuhan 430071, Hubei, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 61期
基金：
中国国家自然科学基金;
关键词：
DRUG-DELIVERY SYSTEM; POLYMERIC MICELLES; NANOPARTICLES; THERAPY; CLUSTERS; NANOGEL;
D O I：
10.1039/c9cc03868j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A simple approach for constructing theranostic nanobeads is developed by using doxorubicin as a phase transfer agent to solubilize small iron oxide nanoclusters. The nanobeads can be specifically internalized into cancer cells with the guidance of an external magnetic field, resulting in good MRI and chemotherapy.
引用
收藏
页码：9015 / 9018
页数：4
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