Synthesis of potential inhibitiors for Stat-3 dimerization

被引：6

作者：

Cui Jia-Rong

Jian Ya-Jun

Wu Yi-Kang

Wang Shao-Meng

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China

[2] NW Univ Xian, Dept Chem, Xian 710069, Shaanxi, Peoples R China

[3] Univ Michigan, Dept Internal Med & Med Chem, Ann Arbor, MI 48109 USA

来源：

CHINESE JOURNAL OF CHEMISTRY | 2006年 / 24卷 / 09期

关键词：

inhibitor; antitumor agent; benzyne; aromatics; angucyclinone;

D O I：

10.1002/cjoc.200690218

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nine bioactive ochromycinone analogues were synthesized through two different types of routes. Some unexpected products were obtained in the photo-induced oxidation. The syntheses disclosed herein complement those in the literature and offer inexpensive access to many of the known intermediates involved, most of which were studied years ago in completely different contexts.

引用

页码：1163 / 1169

页数：7

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