Review of preclinical and clinical studies of using cell-based therapy for secondary lymphedema

被引:15
作者
Chen, Ching-En [1 ,2 ]
Chiang, Nai-Jung [3 ,4 ]
Perng, Cherng-Kang [1 ,2 ]
Ma, Hsu [1 ,2 ]
Lin, Chih-Hsun [1 ,2 ]
机构
[1] Taipei Vet Gen Hosp, Div Plast & Reconstruct Surg, Dept Surg, 19F,201,Sec 2,Shi Pei St, Taipei 112, Taiwan
[2] Natl Yang Ming Univ, Sch Med, Dept Surg, Taipei, Taiwan
[3] Natl Hlth Res Inst, Natl Inst Canc Res, Tainan, Taiwan
[4] Cheng Kung Univ, Dept Internal Med, Med Ctr, Tainan, Taiwan
关键词
adipose-devised stem cells; cell therapy; lymphangiogenesis; lymphedema; mesenchymal stem cells; MESENCHYMAL STEM-CELLS; LOWER-LIMB LYMPHEDEMA; MARROW STROMAL CELLS; ACUTE LUNG INJURY; DIABETES IMPAIRS; RISK-FACTORS; CANCER; LYMPHANGIOGENESIS; TRANSPLANTATION; LYMPHOSCINTIGRAPHY;
D O I
10.1002/jso.25661
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Secondary lymphedema is associated with impaired lymph fluid drainage and remains incurable. Alternatively, cell-based therapy may pave the way for lymphedema treatment. We found 11 animal and seven human studies had been conducted from 2008 to 2018. Most studies showed great potential for this treatment modality. Emerging studies have focused on novel techniques, such as coupling cell therapy with lymph node transfer, or adding growth factors to cell therapy.
引用
收藏
页码:109 / 120
页数:12
相关论文
共 63 条
[1]   Impact of platelet rich plasma and adipose stem cells on lymphangiogenesis in a murine tail lymphedema model [J].
Ackermann, Maximilian ;
Wettstein, Reto ;
Senaldi, Christopher ;
Kalbermatten, Daniel F. ;
Konerding, Moritz A. ;
Raffoul, Wassim ;
Erba, Paolo .
MICROVASCULAR RESEARCH, 2015, 102 :78-85
[2]   Lymphedema surgery: Patient selection and an overview of surgical techniques [J].
Allen, Robert J., Jr. ;
Cheng, Ming-Huei .
JOURNAL OF SURGICAL ONCOLOGY, 2016, 113 (08) :923-931
[3]  
[Anonymous], 2016, LYMPHOLOGY, V49, P170
[4]   Multipotent Adult Progenitor Cells Support Lymphatic Regeneration at Multiple Anatomical Levels during Wound Healing and Lymphedema [J].
Beerens, Manu ;
Aranguren, Xabier L. ;
Hendrickx, Benoit ;
Dheedene, Wouter ;
Dresselaers, Tom ;
Himmelreich, Uwe ;
Verfaillie, Catherine ;
Luttun, Aernout .
SCIENTIFIC REPORTS, 2018, 8
[5]   Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance [J].
Berry, Mark F. ;
Engler, Adam J. ;
Woo, Y. Joseph ;
Pirolli, Timothy J. ;
Bish, Lawrence T. ;
Jayasankar, Vasant ;
Morine, Kevin J. ;
Gardner, Timothy J. ;
Discher, Dennis E. ;
Sweeney, H. Lee .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2006, 290 (06) :H2196-H2203
[6]   Emerging therapy for improving wound repair of severe radiation burns using local bone marrow-derived stem cell administrations [J].
Bey, Eric ;
Prat, Marie ;
Duhamel, Patrick ;
Benderitter, Marc ;
Brachet, Michel ;
Trompier, Francois ;
Battaglini, Pierre ;
Ernou, Isabelle ;
Boutin, Laetitia ;
Gourven, Muriel ;
Tissedre, Frederique ;
Crea, Sandrine ;
Mansour, Cedric Ait ;
de Revel, Thierry ;
Carsin, Herve ;
Gourmelon, Patrick ;
Lataillade, Jean-Jacques .
WOUND REPAIR AND REGENERATION, 2010, 18 (01) :50-58
[7]   Microsurgical techniques for lymphedema treatment: Derivative lymphatic-venous microsurgery [J].
Campisi, C ;
Boccardo, F .
WORLD JOURNAL OF SURGERY, 2004, 28 (06) :609-613
[8]   Mesenchymal Stem Cells: Time to Change the Name! [J].
Caplan, Arnold I. .
STEM CELLS TRANSLATIONAL MEDICINE, 2017, 6 (06) :1445-1451
[9]   A Prospective Analysis of 100 Consecutive Lymphovenous Bypass Cases for Treatment of Extremity Lymphedema [J].
Chang, David W. ;
Suami, Hiroo ;
Skoracki, Roman .
PLASTIC AND RECONSTRUCTIVE SURGERY, 2013, 132 (05) :1305-1314
[10]   Validity of the Novel Taiwan Lymphoscintigraphy Staging and Correlation of Cheng Lymphedema Grading for Unilateral Extremity Lymphedema [J].
Cheng, Ming-Huei ;
Pappalardo, Marco ;
Lin, Chieh ;
Kuo, Chang-Fu ;
Lin, Chia-Yu ;
Chung, Kevin C. .
ANNALS OF SURGERY, 2018, 268 (03) :513-525