Panels and Syndromic Testing in Clinical Microbiology

被引：55

作者：

Bard, Jennifer Dien ^{[1
,2
]}

McElvania, Erin ^{[3
,4
]}

机构：

[1] Childrens Hosp Los Angeles, Dept Pathol & Lab Med, 4650 Sunset Blvd MS 32, Los Angeles, CA 90027 USA

[2] Univ Southern Calif, Keck Sch Med, Los Angeles, CA 90089 USA

[3] NorthShore Univ HealthSyst, Evanston Hosp, Dept Pathol & Lab Med, 2650 Ridge Ave, Evanston, IL 60201 USA

[4] Univ Chicago, Pritzker Sch Med, Chicago, IL 60637 USA

来源：

CLINICS IN LABORATORY MEDICINE | 2020年 / 40卷 / 04期

关键词：

Syndromic panel; Respiratory panel; Bloodstream infection panel; Gastroenteritis panel; Meningitis panel; Encephalitis panel; Diagnostic stewardship; Laboratory stewardship; BLOOD CULTURE IDENTIFICATION; ANTIMICROBIAL STEWARDSHIP; MULTICENTER EVALUATION; PCR ASSAY; PATHOGEN IDENTIFICATION; RAPID DETECTION; IMPACT; DIAGNOSTICS; BACTERIA; OUTCOMES;

D O I：

10.1016/j.cll.2020.08.001

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Syndromic panels have allowed clinical microbiology laboratories to rapidly identify bacteria, viruses, fungi, and parasites and are now fully integrated into the standard testing practices of many clinical laboratories. To maximize the benefit of syndromic testing, laboratories must implement strict measures to ensure that syndromic panels are being used responsibly. This article discusses commercially available syndromic panels, the benefits and limitations of testing, and how diagnostic and laboratory stewardship can be used to optimize testing and improve patient care while keeping costs at a minimum.

引用

页码：393 / 420

页数：28

共 52 条

[1] Prediction of bacterial meningitis based on cerebrospinal fluid pleocytosis in children [J].

Agueda, Sofia ;

Campos, Teresa ;

Maia, Ana .

BRAZILIAN JOURNAL OF INFECTIOUS DISEASES, 2013, 17 (04) :401-404

[2] Impact of Gastrointestinal Panel Implementation on Health Care Utilization and Outcomes [J].

Axelrad, Jordan E. ;

Freedberg, Daniel E. ;

Whittier, Susan ;

Greendyke, William ;

Lebwohl, Benjamin ;

Green, Daniel A. .

JOURNAL OF CLINICAL MICROBIOLOGY, 2019, 57 (03)

[3] Randomized Trial of Rapid Multiplex Polymerase Chain Reaction-Based Blood Culture Identification and Susceptibility Testing [J].

Banerjee, Ritu ;

Teng, Christine B. ;

Cunningham, Scott A. ;

Ihde, Sherry M. ;

Steckelberg, James M. ;

Moriarty, James P. ;

Shah, Nilay D. ;

Mandrekar, Jayawant N. ;

Patel, Robin .

CLINICAL INFECTIOUS DISEASES, 2015, 61 (07) :1071-1080

[4]

Bard JD, 2018, J CLIN MICROBIOL, V56, DOI [10.1128/jcm.00018-18, 10.1128/JCM.00018-18]

[5] Performance and Impact of the BioFire FilmArray Gastrointestinal Panel on a Large Cyclospora Outbreak in Wisconsin, 2018 [J].

Bateman, Allen C. ;

Kim, Youngmi J. ;

Guaracao, Ana I. ;

Mason, Jordan L. ;

Klos, Rachel F. ;

Warshauer, David M. .

JOURNAL OF CLINICAL MICROBIOLOGY, 2020, 58 (02)

[6]

Beal SG, 2018, J CLIN MICROBIOL, V56, DOI [10.1128/JCM.02012-17, 10.1128/JCM.02029-17]

[7]

Blaschke AJ, 2018, J CLIN MICROBIOL, V56, DOI [10.1128/JCM.00277-18, 10.1128/jcm.00277-18]

[8] Analytical and clinical validation of a microbial cell-free DNA sequencing test for infectious disease [J].

Blauwkamp, Timothy A. ;

Thair, Simone ;

Rosen, Michael J. ;

Blair, Lily ;

Lindner, Martin S. ;

Vilfan, Igor D. ;

Kawli, Trupti ;

Christians, Fred C. ;

Venkatasubrahmanyam, Shivkumar ;

Wall, Gregory D. ;

Cheung, Anita ;

Rogers, Zoe N. ;

Meshulam-Simon, Galit ;

Huijse, Liza ;

Balakrishnan, Sanjeev ;

Quinn, James, V ;

Hollemon, Desiree ;

Hong, David K. ;

Vaughn, Marla Lay ;

Kertesz, Mickey ;

Bercovici, Sivan ;

Wilber, Judith C. ;

Yang, Samuel .

NATURE MICROBIOLOGY, 2019, 4 (04) :663-674

[9] Multicenter Evaluation of the BioFire FilmArray Gastrointestinal Panel for Etiologic Diagnosis of Infectious Gastroenteritis [J].

Buss, Sarah N. ;

Leber, Amy ;

Chapin, Kimberle ;

Fey, Paul D. ;

Bankowski, Matthew J. ;

Jones, Matthew K. ;

Rogatcheva, Margarita ;

Kanack, Kristen J. ;

Bourzac, Kevin M. .

JOURNAL OF CLINICAL MICROBIOLOGY, 2015, 53 (03) :915-925

[10] Impact of a multiplex PCR assay (FilmArray®) on the management of patients with suspected central nervous system infections [J].

Cailleaux, Marine ;

Pilmis, Benoit ;

Mizrahi, Assaf ;

Lourtet-Hascoet, Julie ;

Van, Jean-Claude Nguyen ;

Alix, Lilian ;

Couzigou, Carine ;

Vidal, Barbara ;

Tattevin, Pierre ;

Le Monnier, Alban .

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2020, 39 (02) :293-297

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