Facilitated transport of 5-aminosalicylic acid through bulk liquid membrane

被引:22
作者
Zaharia, Ionut [1 ]
Aboul-Enein, Hassan Y. [2 ]
Diaconu, Ioana [1 ]
Ruse, Elena [1 ]
Bunaciu, Andrei A. [3 ]
Nechifor, Gheoghe [1 ]
机构
[1] Univ Politehn Bucuresti, Dept Analyt Chem, Fac Appl Chem & Mat Sci, Bucharest, Romania
[2] Natl Res Ctr, Pharmaceut & Drug Ind Res Div, Dept Pharmaceut & Med Chem, Cairo 12311, Egypt
[3] SC CROMATEC PLUS SRL, SCIENT Res Ctr Instrumental Anal, Bucharest, Romania
关键词
5-Aminosalicylic acid; Bulk liquid membrane; Aliquat; 336; Kinetic model; PERSONAL CARE PRODUCTS; WASTE-WATER TREATMENT; AMINO-ACIDS; CHROMIUM(VI) IONS; TREATMENT PLANTS; PENICILLIN-G; KINETICS; DRUGS; PHARMACEUTICALS; PERTRACTION;
D O I
10.1007/s13738-013-0245-1
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This paper describes the experimental results obtained at the transport of 5-aminosalicylic acid (5ASA) through agitated bulk liquid membrane, using Aliquat 336, as carrier, dissolved in a chloroform membrane. The influence of 5-aminosalicylic acid concentration in the feed source, HCl concentration in the stripping phase and carrier (Aliquat 336) concentration in the membrane were investigated. The optimal pH condition of feed source was established based on the speciation diagram of 5-aminosalicylic acid. The assessment of the transport process was performed by determining the kinetic parameters-mass transfer coefficient and entrance and exist flow in and out of the chloroform membrane.
引用
收藏
页码:1129 / 1136
页数:8
相关论文
共 42 条
[1]  
ALLGAYER H, 1985, ARZNEIMITTEL-FORSCH, V35-2, P1457
[2]  
Alpoguz HK, 2005, TURK J CHEM, V29, P345
[3]   Effects of acceptor phase and donor phase properties on sodium ions transport from aqueous solutions using liquid membrane systems [J].
Altin, Suereyya ;
Demircioglu, Nuhi ;
Peker, Ibrahim ;
Altin, Ahmet .
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2007, 306 (1-3) :14-21
[4]   Aminosalicylic acid conjugates of EDTA as potential anti-inflammatory pro-drugs: synthesis, copper chelation and superoxide dismutase-like activities [J].
Bailey, Mark A. ;
Ingram, Matthew J. ;
Naughton, Declan P. ;
Rutt, Ken J. ;
Dodd, Howard T. .
TRANSITION METAL CHEMISTRY, 2008, 33 (02) :195-202
[5]  
Balaban A.T., 1999, LITTLE ENCY CHEM TEC, V1
[6]   SEPARATION OF L-VALINE FROM FERMENTATION BROTHS USING A SUPPORTED LIQUID MEMBRANE [J].
DEBLAY, P ;
MINIER, M ;
RENON, H .
BIOTECHNOLOGY AND BIOENGINEERING, 1990, 35 (02) :123-131
[7]  
Diaconu I, 2012, REV CHIM-BUCHAREST, V63, P153
[8]   Separation of nitrophenols. Equilibriums in bi- and tri-phasic systems [J].
Diaconu, Ioana ;
Aboul-Enein, Hassan Y. ;
Al-Omar, Mohammed A. ;
Nechifor, Gheorghe ;
Ruse, Elena ;
Bunaciu, Andrei A. ;
Totu, Eugenia Eftimie .
ARABIAN JOURNAL OF CHEMISTRY, 2011, 4 (01) :99-103
[9]  
Diaconu I, 2009, REV CHIM-BUCHAREST, V60, P1243
[10]   Solvent extraction of dopamine by heptakis (2,3,6-tri-O-acetyl)-β-cyclodextrin [J].
Diacu, Elena ;
Mutihac, Lucia ;
Ruse, Elena ;
Ceausescu, Madalin Marin .
JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY, 2011, 71 (3-4) :339-342