Management of knee osteoarthritis. Current status and future trends

被引：61

作者：

Ondresik, Marta ^{[1
,2
]}

Azevedo Maia, Fatima R. ^{[1
,2
]}

Morais, Alain da Silva ^{[1
,2
,3
]}

Gertrudes, Ana C. ^{[1
,2
,3
]}

Dias Bacelar, Ana H. ^{[1
,2
,3
]}

Correia, Cristina ^{[1
,2
,3
]}

Goncalves, Cristiana ^{[1
,2
,3
]}

Radhouani, Hajer ^{[1
,2
,3
]}

Sousa, Rui Amandi ^{[1
,2
,3
]}

Oliveira, Joaquim M. ^{[1
,2
]}

Reis, Rui L. ^{[1
,2
]}

机构：

[1] Univ Minho, Headquarters European Inst Regenerat Med, Res Grp Biomat Biodegradables & Biomimet 3Bs, Caldas Das Taipas, Guimaraes, Portugal

[2] ICVS 3Bs PT Govt Associated Lab, Braga, Portugal

[3] Stemmatters Biotecnol & Med Regenerat SA, Guimaraes, Portugal

来源：

BIOTECHNOLOGY AND BIOENGINEERING | 2017年 / 114卷 / 04期

关键词：

osteoarthritis; articular cartilage; biomaterials; scaffolds; regeneration; viscosupplementation; gene therapy; tissue engineering; MESENCHYMAL STEM-CELLS; ARTICULAR-CARTILAGE REPAIR; HYALURONIC-ACID HYDROGELS; AUTOLOGOUS CHONDROCYTE IMPLANTATION; GELLAN GUM HYDROGELS; PLATELET-RICH PLASMA; NERVE GROWTH-FACTOR; IN-VITRO; BONE-MARROW; CHONDROGENIC DIFFERENTIATION;

D O I：

10.1002/bit.26182

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Osteoarthritis (OA) affects a large number of the population, and its incidence is showing a growing trend with the increasing life span. OA is the most prevalent joint condition worldwide, and currently, there is no functional cure for it. This review seeks to briefly overview the management of knee OA concerning standardized pharmaceutical and clinical approaches, as well as the new biotechnological horizons of OA treatment. The potential of biomaterials and state of the art of advanced therapeutic approaches, such as cell and gene therapy focused primarily on cartilage regeneration are the main subjects of this review. Biotechnol. Bioeng. 2017;114: 717-739. (c) 2016 Wiley Periodicals, Inc.

引用

页码：717 / 739

页数：23

共 328 条

[1] Detection of human endogenous retrovirus K (HERV-K) transcripts in human prostate cancer cell lines [J].

Agoni, Lorenzo ;

Guha, Chandan ;

Lenz, Jack .

FRONTIERS IN ONCOLOGY, 2013, 3

[2] A comparison of fibrin, agarose and gellan gum hydrogels as carriers of stem cells and growth factor delivery microspheres for cartilage regeneration [J].

Ahearne, Mark ;

Kelly, Daniel J. .

BIOMEDICAL MATERIALS, 2013, 8 (03)

[3] The long-term outcome of high tibial osteotomy - A ten- to 20-year follow-up [J].

Akizuki, S. ;

Shibakawa, A. ;

Takizawa, T. ;

Yamazaki, I. ;

Horiuchi, H. .

JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 2008, 90B (05) :592-596

[4] The potential of intra-articular injection of chondrogenic-induced bone marrow stem cells to retard the progression of osteoarthritis in a sheep model [J].

Al Faqeh, Hamoud ;

Hamdan, Bin Mohamad Yahya Nor ;

Chen, Hui Cheng ;

Aminuddin, Bin Saim ;

Ruszymah, Bt Hj Idrus .

EXPERIMENTAL GERONTOLOGY, 2012, 47 (06) :458-464

[5] Human Stromal (Mesenchymal) Stem Cells from Bone Marrow, Adipose Tissue and Skin Exhibit Differences in Molecular Phenotype and Differentiation Potential [J].

Al-Nbaheen, May ;

Vishnubalaji, Radhakrishnan ;

Ali, Dalia ;

Bouslimi, Amel ;

Al-Jassir, Fawzi ;

Megges, Matthias ;

Prigione, Alessandro ;

Adjaye, James ;

Kassem, Moustapha ;

Aldahmash, Abdullah .

STEM CELL REVIEWS AND REPORTS, 2013, 9 (01) :32-43

[6] Culture of chondrocytes in alginate surrounded by fibrin gel: characteristics of the cells over a period of eight weeks [J].

Almqvist, KF ;

Wang, L ;

Wang, J ;

Baeten, D ;

Cornelissen, M ;

Verdonk, R ;

Veys, EM ;

Verbruggen, G .

ANNALS OF THE RHEUMATIC DISEASES, 2001, 60 (08) :781-790

[7] Silk-based biomaterials [J].

Altman, GH ;

Diaz, F ;

Jakuba, C ;

Calabro, T ;

Horan, RL ;

Chen, JS ;

Lu, H ;

Richmond, J ;

Kaplan, DL .

BIOMATERIALS, 2003, 24 (03) :401-416

[8] Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage - Influence of nitric oxide [J].

Amin, AR ;

Attur, M ;

Patel, RN ;

Thakker, GD ;

Marshall, PJ ;

Rediske, J ;

Stuchin, SA ;

Patel, IR ;

Abramson, SB .

JOURNAL OF CLINICAL INVESTIGATION, 1997, 99 (06) :1231-1237

[9] Engineered recombinant bacterial collagen as an alternative collagen-based biomaterial for tissue engineering [J].

An, Bo ;

Kaplan, David L. ;

Brodsky, Barbara .

FRONTIERS IN CHEMISTRY, 2014, 2

[10] Biodegradation and biocompatibility of PLA and PLGA microspheres [J].

Anderson, James M. ;

Shive, Matthew S. .

ADVANCED DRUG DELIVERY REVIEWS, 2012, 64 :72-82

← 1 2 3 4 5 6 7 8 9 10 →