Nomogram based on clinical features at a single outpatient visit to predict masked hypertension and masked uncontrolled hypertension: A study of diagnostic accuracy

被引:2
作者
Meng, Hong [1 ,2 ,3 ]
Guo, Liang [1 ,2 ,3 ]
Kong, Bin [1 ,2 ,3 ]
Shuai, Wei [1 ,2 ,3 ]
Huang, He [1 ,2 ,3 ,4 ]
机构
[1] Wuhan Univ, Dept Cardiol, Renmin Hosp, Wuhan, Hubei, Peoples R China
[2] Wuhan Univ, Cardiovasc Res Inst, Wuhan, Hubei, Peoples R China
[3] Hubei Key Lab Cardiol, Wuhan, Hubei, Peoples R China
[4] Wuhan Univ, Dept Cardiol, Renmin Hosp, 238 Jiefang Rd, Wuhan 430060, Hubei, Peoples R China
基金
中国国家自然科学基金;
关键词
masked hypertension; masked uncontrolled hypertension; nomogram; prediction model; BLOOD-PRESSURE; NOCTURNAL HYPERTENSION; EUROPEAN-SOCIETY;
D O I
10.1097/MD.0000000000032144
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Patients with masked hypertension (MH) and masked uncontrolled hypertension (MUCH) are easily overlooked, and both cause target organ damage. We propose a prediction model for MH and MUCH patients based on clinical features at a single outpatient visit. Data collection was planned before the index test and reference standard were after. Thus, we retrospectively collect analyzed 804 subjects who underwent ambulatory blood pressure monitoring (ABPM) at Renmin Hospital of Wuhan University. These patients were divided into normotension/controlled hypertension group (n = 121), MH/MUCH (n = 347), and sustained hypertension (SH)/sustained uncontrolled hypertension group (SUCH) (n = 302) for baseline characteristic analysis. Models were constructed by logistic regression, a nomogram was visualized, and internal validation by bootstrapping. All groups were performed according to the definition proposed by the Chinese Hypertension Association. Compared with normotension/controlled hypertension, patients with MH/MUCH had higher office blood pressure (BP) and were more likely to have poor liver and kidney function, metabolic disorder and myocardial damage. By analysis, [office systolic blood pressure (OSBP)] (P = .004) and [office diastolic blood pressure (ODBP)] (P = .007) were independent predictors of MH and MUCH. By logistic regression backward stepping method, office BP, body mass index (BMI), total cholesterol (Tch), high-density lipoprotein cholesterol (HDL-C), and left ventricular mass index are contained in this model [area under curve (AUC) = 0.755] and its mean absolute error is 0.015. Therefore, the prediction model established by the clinical characteristics or relevant data obtained from a single outpatient clinic can accurately predict MH and MUCH.
引用
收藏
页数:7
相关论文
共 40 条
[1]   2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension [J].
Afridi, I ;
Canny, J ;
Yao, CH ;
Christensen, B ;
Cooper, RS ;
Kadiri, S ;
Hill, S ;
Kaplan, N ;
Kuschnir, E ;
Lexchin, J ;
Mendis, S ;
Poulter, N ;
Psaty, BM ;
Rahn, KH ;
Sheps, SG ;
Whitworth, J ;
Yach, D ;
Bengoa, R ;
Ramsay, L ;
Kaplan, N ;
Mendis, S ;
Poulter, N ;
Whitworth, J .
JOURNAL OF HYPERTENSION, 2003, 21 (11) :1983-1992
[2]  
[Anonymous], 2010, Fact sheet on wheelchairs
[3]   Setting Thresholds to Varying Blood Pressure Monitoring Intervals Differentially Affects Risk Estimates Associated With White-Coat and Masked Hypertension in the Population [J].
Asayama, Kei ;
Thijs, Lutgarde ;
Li, Yan ;
Gu, Yu-Mei ;
Hara, Azusa ;
Liu, Yan-Ping ;
Zhang, Zhenyu ;
Wei, Fang-Fei ;
Lujambio, Ines ;
Mena, Luis J. ;
Boggia, Jose ;
Hansen, Tine W. ;
Bjoerklund-Bodegard, Kristina ;
Nomura, Kyoko ;
Ohkubo, Takayoshi ;
Jeppesen, Jorgen ;
Torp-Pedersen, Christian ;
Dolan, Eamon ;
Stolarz-Skrzypek, Katarzyna ;
Malyutina, Sofia ;
Casiglia, Edoardo ;
Nikitin, Yuri ;
Lind, Lars ;
Luzardo, Leonella ;
Kawecka-Jaszcz, Kalina ;
Sandoya, Edgardo ;
Filipovsky, Jan ;
Maestre, Gladys E. ;
Wang, Jiguang ;
Imai, Yutaka ;
Franklin, Stanley S. ;
O'Brien, Eoin ;
Staessen, Jan A. .
HYPERTENSION, 2014, 64 (05) :935-+
[4]   High prevalence of masked uncontrolled hypertension in people with treated hypertension [J].
Banegas, Jose R. ;
Ruilope, Luis M. ;
de la Sierra, Alejandro ;
de la Cruz, Juan J. ;
Gorostidi, Manuel ;
Segura, Julian ;
Martell, Nieves ;
Garcia-Puig, Juan ;
Deanfield, John ;
Williams, Bryan .
EUROPEAN HEART JOURNAL, 2014, 35 (46) :3304-3312
[5]   Isolated ambulatory hypertension predicts cardiovascular morbidity in elderly men [J].
Björklund, K ;
Lind, L ;
Zethelius, B ;
Andrén, B ;
Lithell, H .
CIRCULATION, 2003, 107 (09) :1297-1302
[6]   Awareness, Knowledge, and Attitudes Toward Screening and Treatment of Masked Hypertension in Primary Care [J].
Boyd, Rebekah ;
Carter, Eileen ;
Moise, Nathalie ;
Alcantara, Carmela ;
Valadares, Thais ;
Anstey, D. Edmund ;
Kronish, Ian M. .
AMERICAN JOURNAL OF HYPERTENSION, 2021, 34 (12) :1322-1327
[7]   Arterial hypertension [J].
Brouwers, Sofie ;
Sudano, Isabella ;
Kokubo, Yoshihiro ;
Sulaica, Elisabeth M. .
LANCET, 2021, 398 (10296) :249-261
[8]   Effects of white-coat, masked and sustained hypertension on coronary artery stenosis and cardiac arrhythmia [J].
Cai, Peng ;
Zhong, Weitian ;
Wang, Yan ;
Wang, Xukai .
HYPERTENSION RESEARCH, 2020, 43 (02) :121-131
[9]   The influence of long-term administration of SGLT2 inhibitors on blood pressure at the office and at home in patients with type 2 diabetes mellitus and chronic kidney disease [J].
Furuki, Takayuki ;
Kobayashi, Kazuo ;
Toyoda, Masao ;
Hatori, Nobuo ;
Sakai, Hiroyuki ;
Sato, Kazuyoshi ;
Miyakawa, Masaaki ;
Tamura, Kouichi ;
Kanamori, Akira .
JOURNAL OF CLINICAL HYPERTENSION, 2020, 22 (12) :2306-2314
[10]   Contribution of single office aortic systolic blood pressure measurements to the detection of masked hypertension: data from two separate cohorts [J].
Gkaliagkousi, Eugenia ;
Protogerou, Athanase D. ;
Argyris, Antonios A. ;
Koletsos, Nikolaos ;
Triantafyllou, Areti ;
Anyfanti, Panagiota ;
Lazaridis, Antonios ;
Dipla, Konstantina ;
Sfikakis, Petros P. ;
Douma, Stella .
HYPERTENSION RESEARCH, 2021, 44 (02) :215-224