Structure and Biological Activity of Galactomannans from Seed Pods of Two Crotalaria Species

被引：0

作者：

Kodiralieva, F. A. ^{[1
]}

Rakhmanberdyeva, R. K. ^{[1
]}

Shevchenko, L. I. ^{[2
]}

Shadybekova, O. B. ^{[2
]}

机构：

[1] Acad Sci Uzbek, S Yu Yunusov Inst Chem Plant Subst, Tashkent, Uzbekistan

[2] Minist Hlth Republ Uzbekistan, Sci Res Inst Hematol & Blood Transfus, Tashkent, Uzbekistan

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2020年

关键词：

Crotalaria; water-soluble polysaccharides; pectinic substances; C-13 NMR spectra; galactomannans; sulfated derivatives; anticoagulant activity; GLEDITSIA-DELAVAYI; POLYSACCHARIDES;

D O I：

10.1007/s10600-020-03212-x

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Water-soluble polysaccharides and pectinic substances from seed pods of Crotalaria alata L. (Uzbekistan) and Crotalaria sp. (India) were studied. The water-soluble polysaccharides were found to dominate over pectinic substances. Galactomannan GM-SP with a Man:Gal ratio of 4.4:1 was isolated from Crotalaria sp. seed pods. Its main chain consisted of 1,4-beta-bound polymannans with 1,6-alpha-bound galactopyranose side residues. Sulfated derivatives of galactomannan from C. alata were prepared. The supramolecular structures of the galactomannan and its sulfated derivative were studied using electron microscopy. The galactomannan sulfated derivative exhibited anticoagulant activity.

引用

页数：5

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