Asymmetric amino-hydroxylation of dienylsilanes. An efficient route to amino-cyclitols.

被引：40

作者：

Angelaud, R

Landais, Y

Schenk, K

机构：

[1] UNIV LAUSANNE,INST CHIM ORGAN,COLL PROPEDEUT,CH-1015 LAUSANNE,SWITZERLAND

[2] UNIV LAUSANNE,INST CRISTALLOG,CH-1015 LAUSANNE,SWITZERLAND

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 08期

关键词：

D O I：

10.1016/S0040-4039(97)00079-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sharpless asymmetric amino-hydroxylation of a silyl-2,5-cyclohexadiene occurs with complete regio- and diastereocontrol. An enantioselectivity of up td 68% e.e. was also observed. An application of the methodology to the synthesis of relevant examples of aminocyclitols is described. (C) 1997 Elsevier Science Ltd.

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页码：1407 / 1410

页数：4

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