Brain Stimulation Improves Cognitive Control by Modulating Medial-Frontal Activity and preSMA-vmPFC Functional Connectivity

被引：56
作者：
Yu, Jiaxin [1 ,2 ]
Tseng, Philip [3 ,4 ]
Hung, Daisy L. [2 ]
Wu, Shih-Wei [1 ]
Juan, Chi-Hung [2 ]
机构：
[1] Natl Yang Ming Univ, Inst Neurosci, Taipei 112, Taiwan
[2] Natl Cent Univ, Inst Cognit Neurosci, Jhongli 320, Taiwan
[3] Taipei Med Univ, Grad Inst Humanities Med, Taipei, Taiwan
[4] Shuang Ho Hosp, Brain & Consciousness Res Ctr, New Taipei City, Taiwan
来源：
HUMAN BRAIN MAPPING | 2015年 / 36卷 / 10期
关键词：
response inhibition; tDCS; fMRI; preSMA; vmPFC; TRANSCRANIAL MAGNETIC STIMULATION; HUMAN MOTOR CORTEX; SIGNAL RESPONSE-INHIBITION; LATERAL PREFRONTAL CORTEX; MEP AMPLITUDE-MODULATION; HEALTHY-HUMAN SUBJECTS; SELF-CONTROL; SUBCORTICAL INTERACTIONS; DECISION-MAKING; MODEL;
D O I：
10.1002/hbm.22893
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Previous research has demonstrated that brain stimulation can improve inhibitory control. However, the neural mechanisms underlying such artificially induced improvement remain unclear. In this study, by coupling anodal transcranial direct current stimulation (atDCS) with functional MRI, we found that atDCS over preSMA effectively improved stopping speed, which was associated with increased BOLD response in the preSMA and ventromedial prefrontal cortex (vmPFC). Furthermore, such atDCS-induced BOLD increase in vmPFC was positively correlated with participants' improvement in stopping efficiency, and the functional connectivity between preSMA and vmPFC increased during successful stop. These results suggest that the rapid behavioral improvement from preSMA brain stimulation involves modulated medial-frontal activity and preSMA-vmPFC functional connectivity. (C) 2015 Wiley Periodicals, Inc.
引用
收藏
页码：4004 / 4015
页数：12
相关论文
共 51 条
  • [1] Conceptual and Procedural Shortcomings of the Systematic Review "Evidence That Transcranial Direct Current Stimulation (tDCS) Generates Little-to-no Reliable Neurophysiologic Effect Beyond MEP Amplitude Modulation in Healthy Human Subjects: A Systematic Review" by Horvath and Co-workers
    Antal, A.
    Keeser, D.
    Priori, A.
    Padberg, F.
    Nitsche, M. A.
    [J]. BRAIN STIMULATION, 2015, 8 (04) : 846 - 849
  • [2] Cortical and subcortical contributions to stop signal response inhibition: Role of the subthalamic nucleus
    Aron, AR
    Poldrack, RA
    [J]. JOURNAL OF NEUROSCIENCE, 2006, 26 (09) : 2424 - 2433
  • [3] Horse-race model simulations of the stop-signal procedure
    Band, GPH
    van der Molen, MW
    Logan, GD
    [J]. ACTA PSYCHOLOGICA, 2003, 112 (02) : 105 - 142
  • [4] Probabilistic independent component analysis for functional magnetic resonance imaging
    Beckmann, CF
    Smith, SA
    [J]. IEEE TRANSACTIONS ON MEDICAL IMAGING, 2004, 23 (02) : 137 - 152
  • [5] Fast oscillations in cortical-striatal networks switch frequency following rewarding events and stimulant drugs
    Berke, J. D.
    [J]. EUROPEAN JOURNAL OF NEUROSCIENCE, 2009, 30 (05) : 848 - 859
  • [6] Training-Induced Changes in Inhibitory Control Network Activity
    Berkman, Elliot T.
    Kahn, Lauren E.
    Merchant, Junaid S.
    [J]. JOURNAL OF NEUROSCIENCE, 2014, 34 (01) : 149 - 157
  • [7] Control of prepotent responses by the superior medial frontal cortex
    Chen, Chiao-Yun
    Muggleton, Neil G.
    Tzeng, Ovid J. L.
    Hung, Daisy L.
    Juan, Chi-Hung
    [J]. NEUROIMAGE, 2009, 44 (02) : 537 - 545
  • [8] A comparison of statistical methods for detecting context-modulated functional connectivity in fMRI
    Cisler, Josh M.
    Bush, Keith
    Steele, J. Scott
    [J]. NEUROIMAGE, 2014, 84 : 1042 - 1052
  • [9] Automaticity in motor sequence learning does not impair response inhibition
    Cohen, Jessica R.
    Poldrack, Russell A.
    [J]. PSYCHONOMIC BULLETIN & REVIEW, 2008, 15 (01) : 108 - 115
  • [10] Executive Functions
    Diamond, Adele
    [J]. ANNUAL REVIEW OF PSYCHOLOGY, VOL 64, 2013, 64 : 135 - 168
123456