Spontaneous remission of low-grade B-cell non-Hodgkin's lymphoma following withdrawal of methotrexate in a patient with rheumatoid arthritis: case report and review of the literature

被引：30
作者：
Baird, RD [1 ]
van Zyl-Smit, RN
Dilke, T
Scott, SE
Rassam, SMB
机构：
[1] Queen Marys Hosp, Dept Haematol, Sidcup DA14 6LR, Kent, England
[2] Queen Marys Hosp, Dept Rheumatol, Sidcup DA14 6LR, Kent, England
[3] Barnard Med Practice, Sidcup, Kent, England
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 2002年 / 118卷 / 02期
关键词：
lymphoma; methotrexate; toxicity; spontaneous regression; rheumatoid arthritis;
D O I：
10.1046/j.1365-2141.2002.03619.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 69-year-old woman, who had suffered from deforming rheumatoid arthritis since the age of 40 years, had been treated with methotrexate for 3 years. She presented with a 7 week history of neck lymphadenopathy. Biopsy revealed low-grade marginal-zone B-cell non-Hodgkin's lymphoma. Computerized tomography and bone marrow biopsy confirmed stage IIIA disease. Spontaneous complete remission of the lymphoma was achieved 14 months after withdrawing immune suppression with methotrexate.
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收藏
页码：567 / 568
页数：2
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