The Impact of Sleep Apnea on Postoperative Utilization of Resources and Adverse Outcomes

被引:141
作者
Memtsoudis, Stavros G. [1 ,2 ]
Stundner, Ottokar [1 ]
Rasul, Rehana [2 ]
Chiu, Ya-Lin [2 ]
Sun, Xuming [2 ]
Ramachandran, Satya-Krishna [3 ]
Kaw, Roop [4 ]
Fleischut, Peter [5 ]
Mazumdar, Madhu [2 ]
机构
[1] Hosp Special Surg, Dept Anesthesiol, New York, NY 10021 USA
[2] Cornell Univ, Weill Med Coll, Dept Publ Hlth, Div Biostat & Epidemiol, New York, NY 10021 USA
[3] Univ Michigan Hlth Syst, Dept Anesthesiol, Ann Arbor, MI USA
[4] Cleveland Clin, Dept Hosp Med, Cleveland, OH 44106 USA
[5] Cornell Univ, Weill Med Coll, NewYork Presbyterian Hosp, Dept Anesthesiol, New York, NY 10021 USA
基金
美国医疗保健研究与质量局;
关键词
KNEE ARTHROPLASTY; SURGICAL-PATIENTS; RISK; COMPLICATIONS; SURGERY; CARE; HIP; ANESTHESIOLOGISTS;
D O I
10.1213/ANE.0000000000000051
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
BACKGROUND: Despite the concern that sleep apnea (SA) is associated with increased risk for postoperative complications, a paucity of information is available regarding the effect of this disorder on postoperative complications and resource utilization in the orthopedic population. With an increasing number of surgical patients suffering from SA, this information is important to physicians, patients, policymakers, and administrators alike. METHODS: We analyzed hospital discharge data of patients who underwent total hip or knee arthroplasty in approximately 400 U.S. Hospitals between 2006 and 2010. Patient, procedure, and health care system-related demographics and outcomes such as mortality, complications, and resource utilization were compared among groups. Multivariable logistic regression models were fit to assess the association between SA and various outcomes. RESULTS: We identified 530,089 entries for patients undergoing total hip and knee arthroplasty. Of those, 8.4% had a diagnosis code for SA. In the multivariate analysis, the diagnosis of SA emerged as an independent risk factor for major postoperative complications (OR 1.47; 95% confidence interval [CI], 1.39-1.55). Pulmonary complications were 1.86 (95% CI, 1.65-2.09) times more likely and cardiac complications 1.59 (95% CI, 1.48-1.71) times more likely to occur in patients with SA. In addition, SA patients were more likely to receive ventilatory support, use more intensive care, stepdown and telemetry services, consume more economic resources, and have longer lengths of hospitalization. CONCLUSIONS: The presence of SA is a major clinical and economic challenge in the postoperative period. More research is needed to identify SA patients at risk for complications and develop evidence-based practices to aid in the allocation of clinical and economic resources.
引用
收藏
页码:407 / 418
页数:12
相关论文
共 31 条
  • [1] Amer Soc Anesthesiologists, 2006, ANESTHESIOLOGY, V104, P1081
  • [2] Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples
    Austin, Peter C.
    [J]. STATISTICS IN MEDICINE, 2009, 28 (25) : 3083 - 3107
  • [3] Preoperative assessment for obstructive sleep apnoea and the prediction of postoperative respiratory obstruction and hypoxaemia
    Blake, D. W.
    Chia, P. H.
    Donnan, G.
    Williams, D. L.
    [J]. ANAESTHESIA AND INTENSIVE CARE, 2008, 36 (03) : 379 - 384
  • [4] MULTIPLE SIGNIFICANCE TESTS - THE BONFERRONI METHOD .10.
    BLAND, JM
    ALTMAN, DG
    [J]. BRITISH MEDICAL JOURNAL, 1995, 310 (6973) : 170 - 170
  • [5] Non-invasive study of airways inflammation in sleep apnea patients
    Carpagnano, Giovanna E.
    Lacedonia, Donato
    Foschino-Barbaro, Maria P.
    [J]. SLEEP MEDICINE REVIEWS, 2011, 15 (05) : 317 - 326
  • [6] Does obstructive sleep apnea increase hematocrit?
    Choi, Jong Bae
    Loredo, Jose S.
    Norman, Daniel
    Mills, Paul J.
    Ancoli-Israel, Sonia
    Ziegler, Michael G.
    Dimsdale, Joel E.
    [J]. SLEEP AND BREATHING, 2006, 10 (03) : 155 - 160
  • [7] Validation of the Berlin questionnaire and American Society of Anesthesiologists checklist as screening tools for obstructive sleep apnea in surgical patients
    Chung, Frances
    Yegneswaran, Balaji
    Liao, Pu
    Chung, Sharon A.
    Vairavanathan, Santhira
    Islam, Sazzadul
    Khajehdehi, Ali
    Shapiro, Colin M.
    [J]. ANESTHESIOLOGY, 2008, 108 (05) : 822 - 830
  • [8] ADAPTING A CLINICAL COMORBIDITY INDEX FOR USE WITH ICD-9-CM ADMINISTRATIVE DATABASES
    DEYO, RA
    CHERKIN, DC
    CIOL, MA
    [J]. JOURNAL OF CLINICAL EPIDEMIOLOGY, 1992, 45 (06) : 613 - 619
  • [9] Prevalence of undiagnosed obstructive sleep apnea among adult surgical patients in an academic medical center
    Finkel, Kevin J.
    Searleman, Adam C.
    Tymkew, Heidi
    Tanaka, Christopher Y.
    Saager, Leif
    Safer-Zadeh, Elika
    Bottros, Michael
    Selvidge, Jacqueline A.
    Jacobsohn, Eric
    Pulley, Debra
    Duntley, Stephen
    Becker, Colleen
    Avidan, Michael S.
    [J]. SLEEP MEDICINE, 2009, 10 (07) : 753 - 758
  • [10] Identification of Patients at Risk for Postoperative Respiratory Complications Using a Preoperative Obstructive Sleep Apnea Screening Tool and Postanesthesia Care Assessment
    Gali, Bhargavi
    Whalen, Francis X.
    Schroeder, Darrell R.
    Gay, Peter C.
    Plevak, David J.
    [J]. ANESTHESIOLOGY, 2009, 110 (04) : 869 - 877