Secondary Hemophagocytic Lymphohistiocytosis (HLH) from a Presumed Brown Recluse Spider Bite

被引：12

作者：

Dandoy, Christopher ^{[1
]}

Grimley, Michael ^{[1
]}

机构：

[1] Cincinnati Childrens Hosp Med Ctr, Dept Pediat, Div Bone Marrow Transplant & Immune Deficiency, Cincinnati, OH 45229 USA

来源：

JOURNAL OF CLINICAL IMMUNOLOGY | 2014年 / 34卷 / 05期

关键词：

Brown recluse spider; systemic loxoscelism; hemophagocytic lymphohistiocytosis (HLH); Loxosceles reclusa;

D O I：

10.1007/s10875-014-0036-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Systemic loxoscelism is a rare complication after Loxosceles reclusa (brown recluse spider) envenomation. Loxosceles venom contains pro-inflammatory proteins, which have been shown to be elevated in patients with hemophagocytic lymph histiocytosis. We present a case of a 10-year-old male that developed presumed systemic loxoscelism, secondary hemophagocytic lymphohistiocytosis with hepatic dysfunction and renal failure. He was treated with dexamethasone and made a full recovery.

引用

页码：544 / 547

页数：4

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