Cyclic voltammetry and electrochemical impedance simulations of the mediator-type enzyme electrode reaction using finite element method

被引：14

作者：

Loew, Noya ^{[1
]}

Ofuji, Takashi ^{[1
]}

Shitanda, Isao ^{[1
]}

Hoshi, Yoshinao ^{[1
,3
]}

Kitazumi, Yuki ^{[2
]}

Kano, Kenji ^{[2
]}

Itagaki, Masayuki ^{[1
]}

机构：

[1] Tokyo Univ Sci, Fac Sci & Technol, Dept Pure & Appl Chem, 2641 Yamazaki, Noda, Chiba 2788510, Japan

[2] Kyoto Univ, Grad Sch Agr, Div Appl Life Sci, Sakyo, Kyoto 6068502, Japan

[3] Nagoya Inst Technol, Dept Phys Sci & Engn, Showa Ku, Nagoya, Aichi 4668555, Japan

来源：

ELECTROCHIMICA ACTA | 2021年 / 367卷

关键词：

Mediator-type enzyme electrode; Cyclic voltammetry; Electrochemical impedance spectroscopy; Electrochemical simulation; Biosensors; SQUARE-WAVE; THEORETICAL TREATMENT; GLUCOSE-OXIDASE; KINETICS; MECHANISM; OXIDATION;

D O I：

10.1016/j.electacta.2020.137483

中图分类号：

O646 [电化学、电解、磁化学];

学科分类号：

081704 ;

摘要：

Simulations enable fundamental electrochemistry to be more deeply understood and are useful tools for the further development of electrochemical processes. However, important parameter restrictions have thus far limited the applicability of electrochemical simulations. In this study, we developed a realistic model of mediator-type enzyme electrodes to accurately simulate cyclic voltammetry and electrochemical impedance spectroscopy by considering the current arising from electrochemical double-layer charging. Implementation of the finite element method in these calculations resulted in a model with very few boundary conditions. The model was successfully tested for various enzyme and electrode reaction kinetics and subsequently adapted to describe immobilized enzymes and mediators. The insight gained through this study has implications for the further development of biosensor and biofuel cell technologies. (C) 2020 The Author(s). Published by Elsevier Ltd.

引用

页数：8

共 31 条

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