Clinical outcomes of the intra-aortic balloon pump for resuscitated patients with acute myocardial infarction complicated by cardiac arrest

被引：9

作者：

Kim, Hyun Kuk ^{[1
]}

Jeong, Myung Ho ^{[1
]}

Ahn, Youngkeun ^{[1
]}

Sim, Doo Sun ^{[1
]}

Chae, Shung Chull ^{[2
]}

Kim, Young Jo ^{[3
]}

Hur, Seung Ho ^{[4
]}

Seong, In Whan ^{[5
]}

Hong, Taek Jong ^{[6
]}

Choi, Dong Hoon ^{[7
]}

Cho, Myeong Chan ^{[8
]}

Kim, Chong Jin ^{[9
]}

Seung, Ki Bae ^{[10
]}

Jang, Yang Soo ^{[7
]}

Rha, Seung Woon ^{[11
]}

Bae, Jang Ho ^{[12
]}

Cho, Jeong Gwan ^{[1
]}

Park, Seung Jung ^{[13
]}

机构：

[1] Chonnam Natl Univ Hosp, Gwangju 501757, South Korea

[2] Kyungpook Natl Univ Hosptial, Daegu, South Korea

[3] Yeungnam Univ Hosp, Daegu, South Korea

[4] Keimyung Univ Hosp, Daegu, South Korea

[5] Chungnam Natl Univ Hosp, Daejeon, South Korea

[6] Busan Natl Univ Hosp, Busan, South Korea

[7] Yonsei Univ, Severans Hosp, Seoul 120749, South Korea

[8] Chungbuk Natl Univ Hosp, Cheongju, South Korea

[9] Kyunghee Univ Hosp, Seoul, South Korea

[10] Catholic Univ Hosp, Seoul, South Korea

[11] Korea Univ Hosp, Seoul, South Korea

[12] Konyang Univ Hosp, Daejeon, South Korea

[13] Ulsan Univ Hosp, Seoul, South Korea

来源：

JOURNAL OF CARDIOLOGY | 2016年 / 67卷 / 1-2期

关键词：

Cardiogenic shock; Myocardial infarction; Intra-aortic balloon pump; PERCUTANEOUS CORONARY INTERVENTION; CARDIOGENIC-SHOCK; EARLY REVASCULARIZATION; BLOOD-FLOW; COUNTERPULSATION; SUPPORT; MANAGEMENT; MORTALITY; IMPACT;

D O I：

10.1016/j.jjcc.2015.04.007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: The aim of this study was to investigate the clinical effects of intra-aortic balloon pump (IABP) in patients who received cardiopulmonary resuscitation (CPR) before procedure. Methods and results: Between November 2005 and April 2014, 49,542 patients were enrolled in a prospective cohort study for acute myocardial infarction (AMI) in Korea (KAMIR). CPR was performed in 1700 patients with cardiac arrest. Patients were excluded from the study if they had not undergone a coronary angiogram, if extracorporeal membrane oxygenation or thrombolysis was performed, and if mechanical complications presented. The primary end point was 1-month all-cause mortality. A total of 883 patients in the IABP group and 476 in the control group were included. During the 1-month followup, all-cause death occurred in 749 patients (55.1%). The IABP group was predominantly male and had a higher prevalence of ST-segment elevation MI and a higher risk of coronary lesions including left main disease and three-vessel disease. Glycoprotein IIb/IIIa inhibitor was administered less in the non-IABP group. In the total population, the IABP group had worse outcomes in terms of mortality rates after multivariate analysis [hazard ratio (HR) 1.22, 95% confidence interval (CI) 1.02-1.47, p = 0.034] without increasing the incidence of recurrent MI, stroke, and major bleeding. After propensity matching with a pair of 452 patients, no significant differences were observed in baseline characteristics or clinical outcomes (HR 1.21, 95% CI 0.93-1.57, p = 0.158). Conclusion: The use of IABP did not show clinical benefits in patients with AMI complicated by severe cardiogenic shock after propensity matching analysis. (C) 2015 Published by Elsevier Ltd on behalf of Japanese College of Cardiology.

引用

页码：57 / 63

页数：7

共 26 条

[1] Comparison of Hospital Mortality With Intra-Aortic Balloon Counterpulsation Insertion Before Versus After Primary Percutaneous Coronary Intervention for Cardiogenic Shock Complicating Acute Myocardial Infarction [J].