Recent developments of chemical imaging sensor systems based on the principle of the light-addressable potentiometric sensor

被引：46

作者：

Yoshinobu, Tatsuo ^{[1
]}

Miyamoto, Ko-ichiro ^{[2
]}

Wagner, Torsten ^{[3
]}

Schoening, Michael J. ^{[3
,4
]}

机构：

[1] Tohoku Univ, Dept Biomed Engn, Aoba Ku, Sendai, Miyagi 9808579, Japan

[2] Tohoku Univ, Dept Elect Engn, Aoba Ku, Sendai, Miyagi 9808579, Japan

[3] Aachen Univ Appl Sci, Inst Nano & Biotechnol, D-52428 Julich, Germany

[4] Res Ctr Julich, Peter Grunberg Inst PGI 8, D-54245 Julich, Germany

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2015年 / 207卷

基金：

日本学术振兴会;

关键词：

Chemical imaging sensor; Light-addressable potentiometric sensor; LAPS; Chemical sensor; Semiconductor; Field effect; SURFACE PHOTOVOLTAGE TECHNIQUE; LAPS SET-UP; HIGH-SPEED; SPATIAL-RESOLUTION; MICROFLUIDIC CHANNEL; QUANTUM DOTS; BIOLOGICAL APPLICATIONS; AMORPHOUS-SILICON; ARRAY; DEVICE;

D O I：

10.1016/j.snb.2014.09.002

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The light-addressable potentiometric sensor (LAPS) is an electrochemical sensor with a field-effect structure to detect the variation of the Nernst potential at its sensor surface, the measured area on which is defined by illumination. Thanks to this light-addressability, the LAPS can be applied to chemical imaging sensor systems, which can visualize the two-dimensional distribution of a particular target ion on the sensor surface. Chemical imaging sensor systems are expected to be useful for analysis of reaction and diffusion in various electrochemical and biological samples. Recent developments of LAPS-based chemical imaging sensor systems, in terms of the spatial resolution, measurement speed, image quality, miniaturization and integration with microfluidic devices, are summarized and discussed. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：926 / 932

页数：7

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