Human challenge pilot study with Cyclospora cayetanensis

被引：23

作者：

Alfano-Sobsey, EM

Eberhard, ML

Seed, JR

Weber, DJ

Won, KY

Nace, EK

Moe, CL

机构：

[1] Off Publ Hlth Preparedness & Response, Raleigh, NC USA

[2] Ctr Dis Control & Prevent, Atlanta, GA USA

[3] Univ N Carolina, Chapel Hill, NC USA

[4] Emory Univ, Atlanta, GA 30322 USA

来源：

EMERGING INFECTIOUS DISEASES | 2004年 / 10卷 / 04期

关键词：

D O I：

10.3201/eid1004.030356

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We describe a pilot study that attempted to infect human volunteers with Cyclospora cayetanensis. Seven healthy volunteers ingested an inoculum of Cyclospora oocysts (approximately 200-49,000 oocysts). The volunteers did not experience symptoms of gastroenteritis, and no oocysts were detected in any stool samples during the 16 weeks volunteers were monitored.

引用

页码：726 / 728

页数：3

共 17 条

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Adam RD, 2000, J CLIN MICROBIOL, V38, P2339

[2]

ASH R, 1991, PARASITES GUIDE LAB

[3] Inactivation of Cryptosporidium parvum oocyst infectivity by disinfection and sterilization processes [J].