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- [41] Mouse macrophages primed with alendronate down-regulate monocyte chemoattractant protein-1 (MCP-1) and macrophage inflammatory protein-1α (MIP-1α) production in response to Toll-like receptor (TLR) 2 and TLR4 agonist via Smad3 activation INTERNATIONAL IMMUNOPHARMACOLOGY, 2009, 9 (09) : 1115 - 1121