New Proteasome Inhibitors

被引:0
作者
Orlowski, Robert Z. [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
关键词
PEGYLATED LIPOSOMAL DOXORUBICIN; MULTIPLE-MYELOMA CELLS; HEMATOLOGIC MALIGNANCIES; BORTEZOMIB; APOPTOSIS; THERAPY; PS-341; TRIAL;
D O I
10.1016/S1557-9190(11)70827-7
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:S43 / S44
页数:2
相关论文
共 11 条
  • [1] A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib
    Chauhan, D
    Catley, L
    Li, GL
    Podar, K
    Hideshima, T
    Velankar, M
    Mitsiades, C
    Mitsiades, N
    Yasui, H
    Letai, A
    Ovaa, H
    Berkers, C
    Nicholson, B
    Chao, TH
    Neuteboom, STC
    Richardson, P
    Palladino, MA
    Anderson, KC
    [J]. CANCER CELL, 2005, 8 (05) : 407 - 419
  • [2] Hideshima T, 2001, CANCER RES, V61, P3071
  • [3] Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myelorna
    Kuhn, Deborah J.
    Chen, Qing
    Voorhees, Peter M.
    Strader, John S.
    Shenk, Kevin D.
    Sun, Congcong M.
    Derno, Susan D.
    Bennett, Mark K.
    Van Leeuwen, Fijs W. B.
    Chanan-Khan, Asher A.
    Orlowski, Robert Z.
    [J]. BLOOD, 2007, 110 (09) : 3281 - 3290
  • [4] Proteasome inhibitors in cancer therapy: Lessons from the first decade
    Orlowski, Robert Z.
    Kuhn, Deborah J.
    [J]. CLINICAL CANCER RESEARCH, 2008, 14 (06) : 1649 - 1657
  • [5] Orlowski RZ, 2007, J CLIN ONCOL, V25, P3892, DOI 10.1200/JCO.2006.10.5460
  • [6] Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies
    Orlowski, RZ
    Stinchcombe, TE
    Mitchell, BS
    Shea, TC
    Baldwin, AS
    Stahl, S
    Adams, J
    Esseltine, DL
    Elliott, PJ
    Pien, CS
    Guerciolini, R
    Anderson, JK
    Depcik-Smith, ND
    Bhagat, R
    Lehman, MJ
    Novick, SC
    O'Connor, OA
    Soignet, SL
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2002, 20 (22) : 4420 - 4427
  • [7] Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies
    Orlowski, RZ
    Voorhees, PM
    Garcia, RA
    Hall, MD
    Kudrik, FJ
    Allred, T
    Johri, AR
    Jones, PE
    Ivanova, A
    Van Deventer, HW
    Gabriel, DA
    Shea, TC
    Mitchell, BS
    Adams, J
    Esseltine, DL
    Trehu, EG
    Green, M
    Lehman, MJ
    Natoli, S
    Collins, JM
    Lindley, CM
    Dees, EC
    [J]. BLOOD, 2005, 105 (08) : 3058 - 3065
  • [8] Bortezomib or high-dose dexamethasone for relapsed multiple myeloma
    Richardson, PG
    Sonneveld, P
    Schuster, MW
    Irwin, D
    Stadtmauer, EA
    Facon, T
    Harousseau, JL
    Ben-Yehuda, D
    Lonial, S
    Goldschmidt, H
    Reece, D
    San-Miguel, JF
    Bladé, J
    Boccadoro, M
    Cavenagh, J
    Dalton, WS
    Boral, AL
    Esseltine, DL
    Porter, JB
    Schenkein, D
    Anderson, KC
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (24) : 2487 - 2498
  • [9] A phase 2 study of bortezomib in relapsed, refractory myeloma
    Richardson, PG
    Barlogie, B
    Berenson, J
    Singhal, S
    Jagannath, S
    Irwin, D
    Rajkumar, SV
    Srkalovic, G
    Alsina, M
    Alexanian, R
    Siegel, D
    Orlowski, RZ
    Kuter, D
    Limentani, SA
    Lee, S
    Hideshima, T
    Esseltine, DL
    Kauffman, M
    Adams, J
    Schenkein, DP
    Anderson, KC
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (26) : 2609 - 2617
  • [10] Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma
    San Miguel, Jesus F.
    Schlag, Rudolf
    Khuageva, Nuriet K.
    Dimopoulos, Meletios A.
    Shpilberg, Ofer
    Kropff, Martin
    Spicka, Ivan
    Petrucci, Maria T.
    Palumbo, Antonio
    Samoilova, Olga S.
    Dmoszynska, Anna
    Abdulkadyrov, Kudrat M.
    Schots, Rik
    Jiang, Bin
    Mateos, Maria-Victoria
    Anderson, Kenneth C.
    Esseltine, Dixie L.
    Liu, Kevin
    Cakana, Andrew
    van de Velde, Helgi
    Richardson, Paul G.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (09) : 906 - 917