MYASTHENIA GRAVIS ASSOCIATED WITH ETANERCEPT THERAPY

被引：38

作者：

Fee, Dominic B. ^{[1
]}

Kasarskis, Edward J. ^{[1
]}

机构：

[1] Univ Kentucky, Dept Neurol, Albert B Chandler Med Ctr, KY Clin, Lexington, KY 40536 USA

来源：

MUSCLE & NERVE | 2009年 / 39卷 / 06期

关键词：

myasthenia gravis; etanercept; pathophysiology; acetylcholine receptor antibodies; Enbrel; ACETYLCHOLINE RECEPTOR ANTIBODIES; PENICILLAMINE-INDUCED MYASTHENIA; MAIN IMMUNOGENIC REGION; RHEUMATOID-ARTHRITIS; MONOCLONAL-ANTIBODIES; FUSION PROTEIN; PATIENT; AUTOANTIBODIES; LOCALIZATION; POLYMORPHISM;

D O I：

10.1002/mus.21280

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Etanercept is an antagonist of tumor necrosis factor alpha that was developed to treat rheumatoid arthritis. In this report we present a patient who developed myasthenia gravis while taking etanercept and had resolution of symptoms after stopping it. This is the first report of this potential side effect and is of additional interest, because etanercept has been proposed as a treatment for myasthenia gravis. Muscle Nerve 39: 866-870, 2009

引用

页码：866 / 870

页数：5

共 47 条

[1] D-PENICILLAMINE INDUCED MYASTHENIA-GRAVIS IN RHEUMATOID-ARTHRITIS - AN UNPREDICTABLE COMMON OCCURRENCE [J].

ANDONOPOULOS, AP ;

TERZIS, E ;

TSIBRI, E ;

PAPASTERIADES, CA ;

PAPAPETROPOULOS, T .

CLINICAL RHEUMATOLOGY, 1994, 13 (04) :586-588

[2] ACETYLCHOLINE-RECEPTOR TURNOVER IN MYASTHENIA-GRAVIS [J].

APPEL, SH ;

BLOSSER, JC ;

MCMANAMAN, JL ;

ASHIZAWA, T .

AMERICAN JOURNAL OF PHYSIOLOGY, 1982, 243 (01) :E31-E36

[3] ACCELERATED DEGRADATION OF ACETYLCHOLINE-RECEPTOR FROM CULTURED RAT MYOTUBES WITH MYASTHENIA-GRAVIS SERA AND GLOBULINS [J].

APPEL, SH ;

ANWYL, R ;

MCADAMS, MW ;

ELIAS, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (05) :2130-2134

[4]

Bal A, 2008, INDIAN J MED RES, V127, P89

[5]

BENDER AN, 1975, LANCET, V1, P607

[6] T-cell tumor necrosis factor-α receptor binding in myasthenic patients [J].

Bongioanni, P ;

Ricciardi, R ;

Pellegrino, D ;

Romano, MR .

JOURNAL OF NEUROIMMUNOLOGY, 1999, 93 (1-2) :203-207

[7] Treatment of experimental autoimmune myasthenia gravis with recombinant human tumor necrosis factor receptor Fc protein [J].

Christadoss, P ;

Goluszko, E .

JOURNAL OF NEUROIMMUNOLOGY, 2002, 122 (1-2) :186-190

[8]

CHRISTENSEN PB, 1995, ACTA NEUROL SCAND, V91, P192

[9] D-PENICILLAMINE AND GOLD SALT TREATMENTS WERE COMPLICATED BY MYASTHENIA AND PEMPHIGUS, RESPECTIVELY, IN THE SAME PATIENT WITH RHEUMATOID-ARTHRITIS [J].

CIOMPI, ML ;

MARCHETTI, G ;

BAZZICHI, L ;

PUCCETTI, L ;

AGELLI, M .

RHEUMATOLOGY INTERNATIONAL, 1995, 15 (03) :95-97

[10] ANTIBODIES TO ACETYLCHOLINE-RECEPTOR IN PATIENTS WITH THYMOMA BUT WITHOUT MYASTHENIA-GRAVIS [J].

CUENOUD, S ;

FELTKAMP, TEW ;

FULPIUS, BW ;

OOSTERHUIS, HJGH .

NEUROLOGY, 1980, 30 (02) :201-203

← 1 2 3 4 5 →