Production of medical 99m Tc isotope via photonuclear reaction

被引：9

作者：

Fujiwara, M. ^{[1
,3
]}

Nakai, K. ^{[1
]}

Takahashi, N. ^{[2
]}

Hayakawa, T. ^{[3
]}

Shizuma, T. ^{[3
]}

Miyamoto, S. ^{[4
]}

Fan, G. T. ^{[4
]}

Takemoto, A. ^{[4
]}

Yamaguchi, M. ^{[4
]}

Nishimura, M. ^{[5
]}

机构：

[1] Osaka Univ, Nucl Phys Res Ctr, Mihogaoka 10-1, Ibaraki, Osaka 5670047, Japan

[2] Osaka Univ, Grad Sch Scinece, Dept Chem, Toyonaka, Osaka 5600043, Japan

[3] Japan Atom Energy Agcy, Shirakata Shirane 2-4, Tokai, Ibaraki 3191195, Japan

[4] Univ Hyogo, Kamigori, Hyogo 6781205, Japan

[5] Kyocera Cooporat, R&D Ctr Kagoshima, Kirishima, Kagoshima 8994312, Japan

来源：

PHYSICS OF PARTICLES AND NUCLEI | 2017年 / 48卷 / 01期

关键词：

TC-99M; TECHNETIUM; MO-99;

D O I：

10.1134/S1063779617010075

中图分类号：

O412 [相对论、场论]; O572.2 [粒子物理学];

学科分类号：

摘要：

(99m) Tc with a 6 hour half-life is one of the most important medical isotopes used for the Single-Photon Emission Computed Tomography (SPECT) inspection in hospitals of US, Canada, Europe and Japan. (99m) Tc isotopes are extracted by the milking method from parent Mo-99 isotopes with a 66 hour half-life. The supply of Mo-99 isotopes now encounters a serious crisis. Hospitals may not suitably receive Mo-99 medical isotopes in near future, due to difficulties in production by research nuclear reactors. Many countries are now looking for alternative ways to generate Mo-99 isotopes other than those with research reactors. We discuss a sustained availability of (99m) Tc isotopes via the (nat) Mo(gamma, n) photonuclear reaction, and discuss to solve technical problems for extracting pure (99m) Tc isotopes from other output materials of photonuclear reactions.

引用

页码：124 / 133

页数：10

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