The green fabrication of nanoparticles (NPs) by using plants as reducing and capping agents involves energy efficient, less toxic, safer and simpler pathways. These pathways have been related to the rational use of numerous substances in fabrication of NPs and synthetic strategies, which have been mainly discussed in this article. The subject matter of this review is to discuss how a chemist can follow the green chemistry principles in terms of selection of substances and protocols used for NPs fabrication. Furthermore, it describes how a researcher can modify the physical properties of NPs by varying the reaction conditions. In short, this review article provides a scheme for the synthesis of NPs from selection of suitable plant to characterization of formed NPs by employing green chemistry.