Updated Phase 1 Results of a First-in-Human Open-Label Study of Lcar-B38M, a Structurally Differentiated Chimeric Antigen Receptor T (CAR- T) Cell Therapy Targeting B-Cell Maturation Antigen (Bcma)

被引：12

作者：

Chen, Lijuan ^{[1
,2
]}

Xu, Jie ^{[1
]}

Fu, Weijun ^{[3
]}

Jin, Shiwei ^{[1
]}

Yang, Shuangshuang ^{[1
]}

Yan, Sun ^{[1
]}

Wu, Wen ^{[1
]}

Liu, Yuanfang ^{[1
]}

Zhang, Wu ^{[1
]}

Weng, Xiangqin ^{[1
]}

Wang, Yan ^{[1
]}

Wang, Jin ^{[5
]}

Ding, Xiaoyi ^{[6
]}

Li, Biao ^{[6
]}

Zhu, Jiang ^{[1
]}

Chen, Zhu ^{[1
]}

Fan, Frank Xiao-Hu ^{[4
]}

Li, Jianyong ^{[2
]}

Hou, Jian ^{[7
]}

Chen, Sai-Juan ^{[1
]}

Mi, Jian-Qing ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Shanghai Inst Hematol, Natl Res Ctr Translat Med, State Key Lab Med Genom,Ruijin Hosp,Sch Med, Shanghai, Peoples R China

[2] Nanjing Med Univ, Dept Hematol, Affiliated Hosp 1, Nanjing, Peoples R China

[3] Shanghai Changzheng Hosp, Dept Hematol, Myeloma Lymphoma Ctr, Shanghai, Peoples R China

[4] Nanjing Legend Biotech, Nanjing, Peoples R China

[5] Shanghai Jiao Tong Univ, Ruijin Hosp, Sch Med, Shanghai, Peoples R China

[6] Shanghai Jiao Tong Univ, Ruijin Hosp, Sch Med, Dept Radiol & Nucl Med, Shanghai, Peoples R China

[7] Shanghai Jiao Tong Univ, Ruijin Hosp, Sch Med, Dept Hematol, Shanghai, Peoples R China

来源：

关键词：

D O I：

10.1182/blood-2019-130008

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

1858

引用

页数：4