Role of atrial structural and functional changes in the development and progression of atrial fibrillation

被引：1

作者：

Aparina, O. P. ^{[1
]}

Chikhireva, L. N. ^{[1
]}

Mironova, N. A. ^{[1
]}

Mironova, E. S. ^{[1
]}

Bakalov, S. A. ^{[1
]}

机构：

[1] Minist Hlth Russia, AL Myasnikov Res Inst Clin Cardiol, Moscow, Russia

来源：

TERAPEVTICHESKII ARKHIV | 2014年 / 86卷 / 01期

关键词：

atrial fibrillation; structural remodeling; inflammation; renin-angiotensin-aldosterone system; ANGIOTENSIN CONVERTING ENZYME; EXTRACELLULAR-MATRIX; GROWTH-FACTOR; ARRHYTHMIA RECURRENCE; CARDIAC FIBROBLASTS; RAT ATRIAL; TGF-BETA; FIBROSIS; SUBSTRATE; INFLAMMATION;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Atrial fibrillation (AF) is one of the most common reasons for decreased life quality and increased mortality rates. Experimental and clinical data show that atrial structural and functional changes contribute to the development and progression of AF. The survey article considers the role of the systemic and local activities of the renin-angiotensin-aldosterone system and inflammatory mediators in the development of atrial structural remodeling, which may be a cause and a consequence of AF.

引用

页码：71 / 77

页数：7

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