Thermal and mechanical characterization of electrospun blends of poly(lactic acid) and poly(glycolic acid)

被引：57
|
作者：
Ramdhanie, Lisa I.
Aubuchon, Steven R.
Boland, Eugene D.
Knapp, Danielle C.
Barnes, Catherine P.
Simpson, David G.
Wnek, Gary E.
Bowlin, Gary L.
机构：
[1] Virginia Commonwealth Univ, Dept Biomed Engn, Richmond, VA 23284 USA
[2] TA Instruments Waters LLC, New Castle, DE 19720 USA
[3] Virginia Commonwealth Univ, Dept Anat & Neurobiol, Richmond, VA 23298 USA
[4] Case Western Reserve Univ, Dept Chem Engn, Cleveland, OH 44106 USA
来源：
POLYMER JOURNAL | 2006年 / 38卷 / 11期
关键词：
poly(glycolic acid); poly(lactic acid); electrospinning; differential scanning calorimetry; polymer blend;
D O I：
10.1295/polymj.PJ2006062
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Poly(lactic acid) (PLA) and poly(glycolic acid) (PGA) have long been popular polymers in the development of tissue engineering scaffolds due to their biocompatibility, bioabsorbability, and good tensile strength. Electrospinning is an attractive approach for the production of non-woven, nano- to micron-scale fibrous tissue engineering scaffolds of complex geometries. In this study, we characterize electrospun blends of PLA and PGA via scanning electron microscopy, tensile testing, differential scanning calorimetry, and phase contrast microscopy to gain a better understanding of these blended structures for potential use in biomedical applications.
引用
收藏
页码：1137 / 1145
页数：9
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