A type III complement factor D deficiency: Structural insights for inhibition of the alternative pathway

被引：11

作者：

Sng, Christopher C. T. ^{[1
]}

O'Byrne, Sorcha ^{[2
]}

Prigozhin, Daniil M. ^{[3
]}

Bauer, Matthias R. ^{[4
]}

Harvey, Jennifer C. ^{[5
]}

Ruhle, Michelle ^{[6
]}

Challis, Ben G. ^{[7
]}

Lear, Sara ^{[2
]}

Roberts, Lee D. ^{[8
]}

Workman, Sarita ^{[5
]}

Janowitz, Tobias ^{[1
]}

Magiera, Lukasz ^{[1
]}

Doffinger, Rainer ^{[2
]}

Buckland, Matthew S. ^{[5
]}

Jodrell, Duncan J. ^{[1
]}

Semple, Robert K. ^{[7
,9
]}

Wilson, Timothy J. ^{[10
]}

Modis, Yorgo ^{[3
]}

Thaventhiran, James E. D. ^{[1
,2
,11
,12
]}

机构：

[1] Canc Res UK Cambridge Inst, Cambridge, England

[2] Addenbrookes Hosp, Cambridge Univ Hosp Natl Hlth Serv Trust, Dept Clin Immunol, Cambridge, England

[3] MRC, Lab Mol Biol, Dept Med, Mol Immun Unit, Cambridge, England

[4] MRC, Lab Mol Biol, Div Struct Studies, Cambridge, England

[5] Royal Free London Natl Hlth Serv Fdn Trust, Dept Immunol, London, England

[6] Walter & Eliza Hall Inst Med Res, Parkville, Vic, Australia

[7] Univ Cambridge, Addenbrookes Hosp, Wellcome Trust MRC Inst Metab Sci, Cambridge, England

[8] Univ Cambridge, Addenbrookes Hosp, Dept Med, Cambridge, England

[9] Univ Leeds, Leeds Inst Cardiovasc & Metab Med, Leeds Inst Genet Hlth & Therapeut LIGHT Labs, Leeds, W Yorkshire, England

[10] Univ Edinburgh, Ctr Cardiovasc Sci, Queens Med Res Inst, Edinburgh, Midlothian, Scotland

[11] Miami Univ, Dept Microbiol, Oxford, OH 45056 USA

[12] Univ Leicester, MRC Toxicol Unit, Leicester, Leics, England

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2018年 / 142卷 / 01期

基金：

英国惠康基金; 英国医学研究理事会;

关键词：

ACTIVATION; FAMILY;

D O I：

10.1016/j.jaci.2018.01.048

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

[No abstract available]

引用

页码：311 / 314

页数：14

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