Combining nanosurface chemistry and microfluidics for molecular analysis and cell biology

被引：40

作者：

Sun, Yi ^{[1
,2
]}

Liu, Yingyi ^{[1
,2
]}

Qu, Weisi ^{[1
,2
]}

Jiang, Xingyu ^{[1
]}

机构：

[1] Natl Ctr NanoSci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China

[2] Chinese Acad Sci, Grad Sch, Beijing 100864, Peoples R China

来源：

ANALYTICA CHIMICA ACTA | 2009年 / 650卷 / 01期

基金：

美国国家科学基金会;

关键词：

Self-assembled monolayer; Microfluidics; Microcontact printing; Soft lithography; Cell patterning; SELF-ASSEMBLED MONOLAYERS; ELECTROSPUN NANOFIBROUS MEMBRANES; ELECTROCHEMICAL DESORPTION; SURFACES; POLY(DIMETHYLSILOXANE); MICROCHANNELS; NANOPARTICLES; FABRICATION; SUBSTRATE; NETWORKS;

D O I：

10.1016/j.aca.2009.05.018

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Development of new tools catalyzes progress in biochemical sciences [G.M. Whitesides, E. Ostuni. S. Takayama, X.Y.Jiang, D.E. Ingber, Annual Review of Biomedical Engineering 3 (2001) 335]. Recent advances in micro-/nano-technology have resulted in an explosion of the number of new tools available for biochemical sciences. We have used surface chemistry, nano-structures and microfluidics to create a set of tools applicable for problems ranging from molecular to cellular analysis. These tools will promote the understanding of fundamental problems in cell biology, development and neurobiology, and become useful for real-world applications such as molecular diagnostics, food analysis and environmental monitoring. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：98 / 105

页数：8

共 44 条

[1]

Abdelgawad M, 2008, LAB CHIP, V8, P672, DOI 10.1039/b801516c

[2]

[Anonymous], 2004, Molecular Biology of the Cell

[3] Geometric determinants of directional cell motility revealed using microcontact printing [J].