Immunotherapeutic targeting of myeloid-derived suppressor cells (MDSCs) activity in obesity-associated cancer

被引：0
作者：
Puttalingaiah, Ramesh Thylur [1 ,2 ]
机构：
[1] Penn State Univ, Coll Med, Dept Biochem & Mol Biol, Hershey, PA USA
[2] Penn State Univ, Coll Med, Dept Biochem & Mol Biol, 500 Univ Dr, Hershey, PA 17033 USA
来源：
ADVANCES IN CANCER BIOLOGY-METASTASIS | 2022年 / 4卷
关键词：
Myeloid -derived suppressor cells; Cancer; Obesity; Immune checkpoint inhibitors; BODY-MASS INDEX; MICROENVIRONMENT;
D O I：
10.1016/j.adcanc.2022.100036
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
[No abstract available]
引用
收藏
页数：3
相关论文
共 26 条
[1]   The opposing roles of CD4+ T cells in anti-tumour immunity [J].
Ahrends, Tomasz ;
Borst, Jannie .
IMMUNOLOGY, 2018, 154 (04) :582-592
[2]   The Complex Interaction between the Tumor Micro-Environment and Immune Checkpoints in Breast Cancer [J].
Barriga, Vanessa ;
Kuol, Nyanbol ;
Nurgali, Kulmira ;
Apostolopoulos, Vasso .
CANCERS, 2019, 11 (08)
[3]   Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression [J].
Bissell, Mina J. ;
Hines, William C. .
NATURE MEDICINE, 2011, 17 (03) :320-329
[4]   Obesity diminishes response to PD-1-based immunotherapies in renal cancer [J].
Boi, Shannon K. ;
Orlandella, Rachael M. ;
Gibson, Justin Tyler ;
Turbitt, William James ;
Wald, Gal ;
Thomas, Lewis ;
Buchta Rosean, Claire ;
Norris, Katlyn E. ;
Bing, Megan ;
Bertrand, Laura ;
Gross, Brett P. ;
Makkouk, Amani ;
Starenki, Dmytro ;
Farag, Kristine, I ;
Sorge, Robert E. ;
Brown, James A. ;
Gordetsky, Jennifer ;
Yasin, Hesham ;
Garje, Rohan ;
Nandagopal, Lakshminarayanan ;
Weiner, George J. ;
Lubaroff, David M. ;
Arend, Rebecca C. ;
Li, Peng ;
Zakharia, Yousef ;
Yang, Eddy ;
Salem, Aliasger K. ;
Nepple, Kenneth ;
Marquez-Lago, Tatiana T. ;
Norian, Lyse A. .
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 8 (02)
[5]   CTLA-4 and PD-1 Pathways Similarities, Differences, and Implications of Their Inhibition [J].
Buchbinder, Elizabeth I. ;
Desai, Anupam .
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2016, 39 (01) :98-106
[6]   Frontline Science: High fat diet and leptin promote tumor progression by inducing myeloid-derived suppressor cells [J].
Clements, Virginia K. ;
Long, Tiha ;
Long, Ramses ;
Figley, Chas ;
Smith, Daniel M. C. ;
Ostrand-Rosenberg, Suzanne .
JOURNAL OF LEUKOCYTE BIOLOGY, 2018, 103 (03) :395-407
[7]   The tumor microenvironment is a dominant force in multidrug resistance [J].
Correia, Ana Luisa ;
Bissell, Mina J. .
DRUG RESISTANCE UPDATES, 2012, 15 (1-2) :39-49
[8]   A multicenter study of body mass index in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors: when overweight becomes favorable [J].
Cortellini, Alessio ;
Bersanelli, Melissa ;
Buti, Sebastiano ;
Cannita, Katia ;
Santini, Daniele ;
Perrone, Fabiana ;
Giusti, Raffaele ;
Tiseo, Marcello ;
Michiara, Maria ;
Di Marino, Pietro ;
Tinari, Nicola ;
De Tursi, Michele ;
Zoratto, Federica ;
Veltri, Enzo ;
Marconcini, Riccardo ;
Malorgio, Francesco ;
Russano, Marco ;
Anesi, Cecilia ;
Zeppola, Tea ;
Filetti, Marco ;
Marchetti, Paolo ;
Botticelli, Andrea ;
Cappellini, Gian Carlo Antonini ;
De Galitiis, Federica ;
Vitale, Maria Giuseppa ;
Rastelli, Francesca ;
Pergolesi, Federica ;
Berardi, Rossana ;
Rinaldi, Silvia ;
Tudini, Marianna ;
Silva, Rosa Rita ;
Pireddu, Annagrazia ;
Atzori, Francesco ;
Chiari, Rita ;
Ricciuti, Biagio ;
De Giglio, Andrea ;
Iacono, Daniela ;
Gelibter, Alain ;
Occhipinti, Mario Alberto ;
Parisi, Alessandro ;
Porzio, Giampiero ;
Fargnoli, Maria Concetta ;
Ascierto, Paolo Antonio ;
Ficorella, Corrado ;
Natoli, Clara .
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7
[9]   Contribution of Adipose Tissue to Development of Cancer [J].
Cozzo, Alyssa J. ;
Fuller, Ashley M. ;
Makowski, Liza .
COMPREHENSIVE PHYSIOLOGY, 2018, 8 (01) :237-282
[10]   Tim-3 and its role in regulating anti-tumor immunity [J].
Das, Madhumita ;
Zhu, Chen ;
Kuchroo, Vijay K. .
IMMUNOLOGICAL REVIEWS, 2017, 276 (01) :97-111
123