Liver Transplant for Cholangiocarcinoma

被引：51
作者：
Zamora-Valdes, Daniel [1 ]
Heimbach, Julie K. [1 ]
机构：
[1] Mayo Clin, Div Transplantat Surg, 200 First St, Rochester, MN 55905 USA
来源：
GASTROENTEROLOGY CLINICS OF NORTH AMERICA | 2018年 / 47卷 / 02期
关键词：
Liver transplantation; Liver cancer; Neoadjuvant radiotherapy; Hilar cholangiocarcinoma; Intrahepatic cholangiocarcinoma; PRIMARY SCLEROSING CHOLANGITIS; SINGLE-CENTER EXPERIENCE; BILE-DUCT CARCINOMA; RESECTABLE PERIHILAR CHOLANGIOCARCINOMA; PORTAL-VEIN EMBOLIZATION; IN-SITU HYBRIDIZATION; LONG-TERM SURVIVAL; INTRAHEPATIC CHOLANGIOCARCINOMA; HILAR CHOLANGIOCARCINOMA; HEPATOCELLULAR-CARCINOMA;
D O I：
10.1016/j.gtc.2018.01.002
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Liver transplant (LT) for perihilar cholangiocarcinoma (CCA) offers an opportunity for survival among patients with early-stage but anatomically unresectable disease. The 5-year survival rate after LT is 65% to 70%, higher among patients with primary sclerosing cholangitis, who are often diagnosed earlier, and lower among patients with de novo CCA. The results of LT for hilar CCA, along with recent limited data suggesting favorable survival among patients with very early intrahepatic CCA (ICC), have reignited interest in the subject. This article discusses LT following neoadjuvant therapy for CCA and the early data on LT alone for ICC.
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页码：267 / +
页数：15
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