Lipid Matrices Destabilization Induced by Some Newly Synthesized Pyridinium Salts

被引：1
|
作者：
Luchese, Angelica M. [1 ]
Di Vitta, Claudio [2 ]
Marzorati, Liliana [2 ]
Yamaoka, Patricia [2 ]
Funari, Sergio S. [3 ]
机构：
[1] Univ Estadual Feira De Santana, Area Quim, Dept Ciencias Exatas, BR-44031460 Feira De Santana, BA, Brazil
[2] Univ Sao Paulo, Inst Quim, Av Lineu Prestes 748, BR-05508900 Sao Paulo, Brazil
[3] HASYLAB DESY, Notkestr 85, D-22607 Hamburg, Germany
来源：
CHEMISTRYSELECT | 2017年 / 2卷 / 04期
关键词：
lipids; membranes; micelles; phase transitions; pyridinium salt; CATIONIC LIPIDS; PHASE; DNA;
D O I：
10.1002/slct.201601588
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The influence of some newly synthesized pyridinium salts on the structural behavior of two lipid matrices formed with POPC or POPE was investigated by using SAXD. The structural impact / evolution of temperature scans were determined on samples prepared with different pyridinium salts / lipid helper molar ratio compositions, in water. In POPC based samples most complexes showed a strong sensitivity to the presence of pyridinium salts, mostly destructive of the long range order. A clear dependence of the structural behavior was correlated with pyridinium salt concentration. In POPE based samples the conformation of the hydrophobic part of such pyridinium salts seems to have a significant impact on the overall matrix structural behavior.
引用
收藏
页码：1491 / 1496
页数：6
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