Role of clinical oncology pharmacist in determination of pharmaceutical care needs in patients with colorectal cancer

被引:13
作者
Tezcan, Songul [1 ]
Izzettin, Fikret Vehbi [1 ]
Sancar, Mesut [1 ]
Turhal, Nazim Serdar [2 ]
Yumuk, Perran Fulden [3 ]
机构
[1] Univ Marmara, Dept Clin Pharm, Fac Pharm, Istanbul, Turkey
[2] Anadolu Med Ctr, Div Med Oncol, Dept Internal Med, Kocaeli, Turkey
[3] Marmara Univ, Div Med Oncol, Dept Internal Med, Sch Med, Istanbul, Turkey
关键词
Colorectal cancer; clinical oncology pharmacist; pharmaceutical care; quality of life; drug related problems; QUALITY-OF-LIFE; CHEMOTHERAPY; NEUROTOXICITY; OUTCOMES; ANEMIA;
D O I
10.1136/ejhpharm-2016-001188
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Objective To determine and evaluate the pharmaceutical care needs and quality of life of patients with colorectal cancer. Methods 36 Patients with colorectal cancer eligible for chemotherapy after surgery were included in the study. The patients were followed up during 3 courses of chemotherapy and individual pharmaceutical care plans were developed. The quality of life of patients was evaluated before and after the third course of chemotherapy. Results The incidence of drug-related problems (DRPs) in chemotherapy-treated patients was reduced in the 3rd course as compared with 1st course (63.9% vs 75%, respectively; n = 36; p > 0.05). The clinical oncology pharmacist gave 147 recommendations to patients, which were followed in 98% (n = 144) of cases. 91.7% (n = 132) of the recommendations of clinical oncology pharmacists solved the drug-related problems; however, the remaining 8.3% (n = 12) did not solve the problems and the patients were referred to a doctor for further investigations. The symptom-related quality of life of patients related to anaemia, diarrhoea and neurotoxicity was reduced after the third course of chemotherapy (p < 0.05). Conclusions The pharmaceutical care provided by the clinical oncology pharmacist has an important role in the identification and resolution of DRPs. Evaluation of symptom-related quality of life is important for the monitoring of patients receiving chemotherapy.
引用
收藏
页码:E17 / E20
页数:4
相关论文
共 24 条
[1]   Pharmaceutical Care: the PCNE definition 2013 [J].
Allemann, Samuel S. ;
van Mil, J. W. Foppe ;
Botermann, Lea ;
Berger, Karin ;
Griese, Nina ;
Hersberger, Kurt E. .
INTERNATIONAL JOURNAL OF CLINICAL PHARMACY, 2014, 36 (03) :544-555
[2]   Restrictions in quality of life in colorectal cancer patients over three years after diagnosis: A population based study [J].
Arndt, Volker ;
Merx, Henrike ;
Stegmaier, Christa ;
Ziegler, Hartwig ;
Brenner, Hermann .
EUROPEAN JOURNAL OF CANCER, 2006, 42 (12) :1848-1857
[3]  
Ayalew Sisay E., 2015, J Cancer Sci Ther, V07, P55, DOI 10.4172/1948-5956.1000325
[4]  
Cella D, 1998, SEMIN ONCOL, V25, P43
[5]   Symptoms, self-care, and quality of life of Chinese American patients with cancer [J].
Chou, Fang-yu ;
Dodd, Marylin ;
Abrams, Donald ;
Padilla, Geraldine .
ONCOLOGY NURSING FORUM, 2007, 34 (06) :1162-1167
[6]  
Dehkordi Ali, 2009, Oman Med J, V24, P204, DOI 10.5001/omj.2009.40
[7]  
Delpeuch A, 2015, ANTICANCER RES, V35, P457
[8]   Satisfaction with information and quality of life in patients undergoing chemotherapy for cancer - The role of individual differences in information preference [J].
Elf, M ;
Wikblad, K .
CANCER NURSING, 2001, 24 (05) :351-356
[9]   Prevention of oxaliplatin-related neurotoxicity by calcium and magnesium infusions:: A retrospective study of 161 patients receiving oxaliplatin combined with 5-fluorouracil and leucovorin for advanced colorectal cancer [J].
Gamelin, L ;
Boisdron-Celle, M ;
Delva, R ;
Guérin-Meyer, V ;
Ifrah, N ;
Morel, A ;
Gamelin, E .
CLINICAL CANCER RESEARCH, 2004, 10 (12) :4055-4061
[10]   Chemotherapy-induced anemia in adults: Incidence and treatment [J].
Groopman, JE ;
Itri, LM .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1999, 91 (19) :1616-1634