Role of ribavirin in membranoproliferative glomerulonephritis associated with hepatitis C virus infection refractory to alpha-interferon

被引：2

作者：

Pérez-Calvo, J

Lasierra, P

Moros, M

Iñigo, P

机构：

[1] Hosp Clin Univ Lozano Blesa, Med Interna Serv, Dept Internal Med, E-50009 Zaragoza, Spain

[2] Hosp Clin Univ Lozano Blesa, Dept Immunol, E-50009 Zaragoza, Spain

[3] Hosp Clin Univ Lozano Blesa, Dept Pathol, E-50009 Zaragoza, Spain

[4] Hosp Clin Barcelona, Dept Nephrol, Barcelona, Spain

来源：

NEPHRON | 2002年 / 92卷 / 02期

关键词：

membranoproliferative glomerulonephritis chronic hepatitis; hepatitis C virus infection; alpha-interferon; ribavirin;

D O I：

10.1159/000063289

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Chronic hepatitis C virus (HCV) has been associated with several extrahepatic diseases, such as membranoproliferative glomerulonephritis (MPGN). a-interferon is currently the treatment of choice for this association. When this therapy fails clinicians face a difficult challenge due to the lack of useful information in these particularly difficult patients. We report the case of a severe nephrotic syndrome due to MPGN associated HCV infection, in which a triple association - interferon plus ribavirin and cyclophosphamide - was needed to control the disease. Copyright (C) 2002 S. Karger AG, Basel.

引用

页码：459 / 462

页数：4

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