Effectiveness of Electroconvulsive Therapy for Refractory Status Epilepticus in Febrile Infection-Related Epilepsy Syndrome

被引：35

作者：

Miras Veiga, Alicia ^{[1
]}

Conejo Moreno, David ^{[2
]}

Gomez Menendez, Ana Isabel ^{[3
]}

Munoz Siscart, Ignacio ^{[4
]}

Del Olmo Fernandez, Marta ^{[5
]}

Gomez Sanchez, Esteban ^{[1
]}

Garcia Gonzalez, Maria ^{[1
]}

Gomez Saez, Fernando ^{[1
]}

机构：

[1] Hosp Univ Burgos, Dept Pediat Intens Care Unit, Avda Islas Baleares 3, Burgos 09006, Spain

[2] Hosp Univ Burgos, Dept Pediat Neurol, Burgos, Spain

[3] Hosp Univ Burgos, Dept Neurophysiol, Burgos, Spain

[4] Hosp Univ Burgos, Dept Psychiat, Burgos, Spain

[5] Hosp Rio Carrion, Dept Pediat, Palencia, Spain

来源：

NEUROPEDIATRICS | 2017年 / 48卷 / 01期

关键词：

FIRES; children; status epilepticus; refractory; electroconvulsive therapy; KETOGENIC DIET; SYNDROME FIRES; CHILDREN; ENCEPHALOPATHY;

D O I：

10.1055/s-0036-1584939

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Febrile infection-related epilepsy syndrome (FIRES) is a rare condition which evolves into refractory status epilepticus (SE), with poor outcome in most cases. Conventional antiepileptic drugs fail to control SE in FIRES patients. We report the case of a previously healthy 4-year-old boy who was diagnosed with FIRES. One week after pharyngitis and high fever he started seizures, followed by refractory SE. Benzodiazepines, phenytoin, high-dose barbiturates that induce burst suppression, high doses of corticosteroids, plasmapheresis, immunoglobulins, propofol, lidocaine, ketamine, inhaled desflurane, ketogenic diet, lacosamide, and therapeutic hypothermiawere tried at different times in a period of 8 weeks, but all of themwere ineffective. Electroconvulsive therapy (ECT) has been used in refractory SE in children. We report a case in which ECT was successfully

引用

页码：45 / 48

页数：4

共 12 条

[1] Lidocaine Treatment in Refractory Status Epilepticus Resulting from Febrile Infection-Related Epilepsy Syndrome: A Case Report and Follow-Up [J].

Capizzi, Giorgio ;

Vittorini, Roberta ;

Torta, Francesca ;

Davico, Chiara ;

Raino, Elena ;

Conio, Alessandra ;

Longobardo, Annalisa ;

Briatore, Eleonora ;

Podesta, Barbara ;

Calzolari, Stefano .

NEUROPEDIATRICS, 2015, 46 (01) :65-68

[2] Febrile infection-related epilepsy syndrome: A study of 12 patients [J].

Caraballo, Roberto H. ;

Reyes, Gabriela ;

Lopez Avaria, Maria Francisca ;

Celeste Buompadre, Maria ;

Gonzalez, Mariana ;

Fortini, Sebastian ;

Cersosimo, Ricardo .

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2013, 22 (07) :553-559

[3] Electroconvulsive therapy for treatment of intractable seizures - Initial findings in two children [J].

Griesemer, DA ;

Kellner, CH ;

Beale, MD ;

Smith, GM .

NEUROLOGY, 1997, 49 (05) :1389-1392

[4] Electroconvulsive Therapy for Refractory Status Epilepticus: A Case Series [J].

Kamel, Hooman ;

Cornes, Susannah Brock ;

Hegde, Manu ;

Hall, Stephen E. ;

Josephson, S. Andrew .

NEUROCRITICAL CARE, 2010, 12 (02) :204-210

[5] Febrile infection-related epilepsy syndrome (FIRES): Pathogenesis, treatment, and outcome A multicenter study on 77 children [J].

Kramer, Uri ;

Chi, Ching-Shiang ;

Lin, Kuang-Lin ;

Specchio, Nicola ;

Sahin, Mustafa ;

Olson, Heather ;

Nabbout, Rima ;

Kluger, Gerhard ;

Lin, Jainn-Jim ;

van Baalen, Andreas .

EPILEPSIA, 2011, 52 (11) :1956-1965

[6] Efficacy of ketogenic diet in severe refractory status epilepticus initiating fever induced refractory epileptic encephalopathy in school age children (FIRES) [J].

Nabbout, Rima ;

Mazzuca, Michel ;

Hubert, Philippe ;

Peudennier, Sylviane ;

Allaire, Catherine ;

Flurin, Vincent ;

Aberastury, Marina ;

Silva, Walter ;

Dulac, Olivier .

EPILEPSIA, 2010, 51 (10) :2033-2037

[7]

Sackeim HA, 1999, J ECT, V15, P5

[8] Successful ECT treatment for medically refractory nonconvulsive status epilepticus in pediatric patient [J].

Shin, Hae W. ;

O'Donovan, Cormac A. ;

Boggs, Jane G. ;

Grefe, Annette ;

Harper, Amy ;

Bell, William L. ;

McCall, W. Vaughn ;

Rosenquist, Peter .

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2011, 20 (05) :433-436

[9] Cognitive Outcomes in Febrile Infection-Related Epilepsy Syndrome Treated With the Ketogenic Diet [J].

Singh, Rani K. ;

Joshi, Sucheta M. ;

Potter, Denise M. ;

Leber, Steve M. ;

Carlson, Martha D. ;

Shellhaas, Renee A. .

PEDIATRICS, 2014, 134 (05) :E1431-E1435

[10] Febrile Infection-Related Epilepsy Syndrome without Detectable Autoantibodies and Response to Immunotherapy: A Case Series and Discussion of Epileptogenesis in FIRES [J].

van Baalen, Andreas ;

Haeusler, Martin ;

Plecko-Startinig, Barbara ;

Strautmanis, Jurgis ;

Vlaho, Stefan ;

Gebhardt, Boris ;

Rohr, Axel ;

Abicht, Angela ;

Kluger, Gerhard ;

Stephani, Ulrich ;

Probst, Christian ;

Vincent, Angela ;

Bien, Christian G. .

NEUROPEDIATRICS, 2012, 43 (04) :209-216

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