Biomolecular assembly by iterative oxime ligations

被引：9
作者：
Renaudet, Olivier [1 ]
Boturyn, Didier [1 ]
Dumy, Pascal [1 ]
机构：
[1] Univ Grenoble 1, Dept Chim Mol, CNRS, UMR 5250,ICMG FR 2607, F-38041 Grenoble 9, France
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2009年 / 19卷 / 14期
关键词：
Glycocluster; Oxime ligation; Bioconjugate; IN-VITRO; B-CELL; PEPTIDE; TEMPLATE; MICROARRAY; PROTEINS; SURFACE; ACCESS; MUC1;
D O I：
10.1016/j.bmcl.2009.03.119
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Herein we describe an iterative oxime-based procedure to prepare multivalent bioconjugates. Our approach is illustrated by the assembly of structurally diverse tetravalent and a new generation of hexadecavalent glycoclusters. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3880 / 3883
页数：4
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