The Ran GTPase: Theme and variations

被引：174

作者：

Dasso, M ^{[1
]}

机构：

[1] NICHD, Lab Gene Regulat & Dev, NIH, Bethesda, MD 20892 USA

来源：

CURRENT BIOLOGY | 2002年 / 12卷 / 14期

关键词：

D O I：

10.1016/S0960-9822(02)00970-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The small GTPase Ran has roles in multiple cellular processes, including nuclear transport, mitotic spindle assembly, the regulation of cell cycle progression and nuclear assembly. The past year has seen a remarkable unification of these different roles with respect to the effectors and mechanisms through which they function. Our emergent understanding of Ran suggests that it plays a central role in spatial and temporal organization of the vertebrate cell.

引用

页码：R502 / R508

页数：7

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